Photo-Characterization of Selective Luminescent Protein Aggregate Sensors-Oligo-p-Phenylene Ethynylene (OPES)

FA Monge - 2020 - search.proquest.com
… aggregate sensing selectivity and sensitivity using model … OPEs sensing of fibrillar and
oligomeric proteins in CSF ............… of two novel oligomeric p-phenylene ethynylenes (OPEs), …

Computational Investigation of the Binding Dynamics of Oligo p-Phenylene Ethynylene Fluorescence Sensors and Aβ Oligomers

TD Martin, G Brinkley, DG Whitten, EY Chi… - ACS chemical …, 2020 - ACS Publications
… a novel class of fluorescence sensors, oligomeric p-phenylene ethynylene (PE)-based
electrolytes (OPEs) selectively bind to and detect prefibrillar and fibrillar aggregates of AD-related …

[HTML][HTML] Well-defined conjugated macromolecules based on oligo (arylene ethynylene) s in sensing

A Krywko-Cendrowska, D Szweda, R Szweda - Processes, 2020 - mdpi.com
… , eg, selective detection of fibrillar and prefibrillar amyloid … p-Phenylene ethynylene oligomers
can be also used for … result in loss of sensor selectivity and sensitivity. Although a variety of …

Controlled and Selective Photo-oxidation of Amyloid-β Fibrils by Oligomeric p-Phenylene Ethynylenes

AM Fanni, D Okoye, FA Monge… - … applied materials & …, 2022 - ACS Publications
… -p-phenylene ethynylenes (OPEs), recently developed for detecting prefibrillar and fibrillar
… T dye could be attributed to its high sensitivity to fluorescence quenching wherein the …

[HTML][HTML] Selective In Vitro and Ex Vivo Staining of Brain Neurofibrillary Tangles and Amyloid Plaques by Novel Ethylene Ethynylene-Based Optical Sensors

FA Monge, AM Fanni, PL Donabedian, J Hulse… - Biosensors, 2023 - mdpi.com
… -p-phenylene ethynylenes (OPEs), anionic OPE 1 2− and cationic OPE 2 4+ , as stains for
fibrillar … phenylene ethynylene (PPE)-based oligomers (OPEs) and polymers (CPEs) for the …

PHOTOPHYSICAL PROPERTIES OF SYNTHETIC OLIGOMERIC PHENYLENE ETHYNYLENE

HF Fritz Jr - 2023 - digitalrepository.unm.edu
… There are multiple uses for Oligomeric Phenylene Ethynylene (… more beneficial method of
detecting Alzheimer's disease early … hope is that consumers with sensitive skin will be drawn to …

Cross-reactive fluorescent sensor array for discrimination of amyloid beta aggregates

P Zhang, C Tan - Analytical Chemistry, 2022 - ACS Publications
… species, namely oligomers, protofibrils, and fibrils, the cross-reactive … CPEs are sensitive to
minor conformational and … structures, such as oligomeric p-phenylene ethynylene (OPE) and …

Protein aggregation detection with fluorescent macromolecular and nanostructured probes: challenges and opportunities

M Cingolani, L Mummolo, F Lugli, M Zaffagnini… - New Journal of …, 2021 - pubs.rsc.org
… Two novel oligomeric p-phenylene ethynylenes (OPEs), … not only for the sensitive and selective
detection of aggregates, but … exploited for the detection of oligomers and fibrils. Recently, …

[HTML][HTML] A Portrait of the OPE as a Biological Agent

CMA Gangemi, A Barattucci, PM Bonaccorsi - Molecules, 2021 - mdpi.com
… to oligomers with an even number of phenylene ethynyleneoligomeric positive compounds
have a good fibril selectivity, … for the detection of saccharides with high sensitivity. In the …

[HTML][HTML] Detection and disaggregation of amyloid fibrils by luminescent amphiphilic platinum (II) complexes

Z Li, AB Ekanayake, AE Bartman, JA Doorn… - Dalton …, 2024 - pubs.rsc.org
detection of mature fibrils, but ThT is not responsive to soluble amyloid oligomers and is not
selective for amyloid fibrils … The metal center in amyloid-sensitive complexes can be utilized …