… Histone deacetylase inhibitors treatment is often accompanied by oxidative stress related
DNA damage that is primarily caused by the generation of reactive oxygen species (ROS) (Xu …

… targets in cancer therapy. As a novel category of antitumor agents, histone deacetylase inhibitors
(HDACis… in cancer cells, ultimately combating cancer. Although in the United States, the …

… important therapeutic benefit. One such approach is to use histone deacetylase inhibitors
(… of targeted therapies, which manipulate the immune response to cancer through epigenetic …

… Surprisingly, in triple-negative breast cancer cells wherein p53 is mutated and its function
is impaired, the histone deacetylase inhibitors (HDACi) were found to induce H2A.Z …

… Histone acetylation, phosphorylation, and methylation are the most prevalent epigenetic …
deregulated in cancer, where histone acetylation is having the most prominent role in cancer (…

… , MB Histone deacetylase inhibitors: recent outcomes from clinical trials and the implications
for oncology treatment … , PA Mechanisms of resistance to histone deacetylase inhibitors. Adv. …

… , histone deacetylase inhibitors (HDACis) are powerful drugs, with some already approved
for certain hematological cancers… NAD + -dependent histone deacetylases similar to the silent …

… Gemcitabine synergizes with the histone deacetylase inhibitor MGCD0103 and they
might be an effective treatment for gemcitabine-refractory pancreatic cancer [151]. …

… histone acetylation and examining the therapeutic potential of histone deacetylase inhibitors
in endometrial cancer. … The search terms histone deacetylase, histone deacetylase inhibitor, …

… options for advanced HCC are extremely limited due to shortage of effective therapeutic …
need for novel therapeutic options is obvious. The role of histone deacetylase inhibitors (HDACIs…