Ovarian cancer: applications of chickens to humans

A Barua, JM Bahr - Annual review of animal biosciences, 2022 - annualreviews.org
Pathology, Histology, and Tumor Type Between Human and … histopathological presentation
of ovarian tumors in human … Thus, the laying hen offers a preclinical model to improve the …

A review of principal studies on the development and treatment of epithelial ovarian cancer in the laying hen Gallus gallus

P Pal, KN Starkweather, KH Hales… - Comparative …, 2021 - ingentaconnect.com
… While developing a reliable animal model is challenging due … , laying hens naturally develop
EOC that is histopathologically … about 90% of ovarian tumors in laying hens express CA125,…

Incidence of malignant transformation in the oviductal fimbria in laying hens, a preclinical model of spontaneous ovarian cancer

EA Paris, JM Bahr, P Bitterman, S Basu… - PLoS …, 2021 - journals.plos.org
… HGSC with histopathologic features seen in many human HGSCs [9, … among hen fimbrial
and ovarian tumors to human ovarian HGSC. All … Histopathological examination of specimens …

Preclinical models of epithelial ovarian cancer: practical considerations and challenges for a meaningful application

A Ciucci, M Buttarelli, A Fagotti, G Scambia… - Cellular and Molecular …, 2022 - Springer
… Advances in our understanding of the histopathology and … zebrafish and the laying hen
models. Recent advances in … developed an ovarian tumour microenvironment chip (OTME-…

Retroviral association with ovarian adenocarcinoma in laying hens

VV Ramoutar, YJ Johnson, LJ Kohrt, JM Bahr… - … Pathology, 2022 - Taylor & Francis
… The domestic laying hen is a useful model for human ovarian carcinoma for many reasons.
Adult female animals of most species, whether domestic or wild, are either persistently …

Inflammasome expression is higher in ovarian tumors than in normal ovary

J Luborsky, A Barua, S Edassery, JM Bahr… - PLoS …, 2020 - journals.plos.org
… the hen, an animal model of spontaneous human ovarian cancer, … tumor ovary structures
was based on our prior studies of ovarian tumor histology [23] and immune cells [24] in the hen. …

[PDF][PDF] … 16-(IL-16-) Targeted Ultrasound Imaging Agent Improves Detection of Ovarian Tumors in Laying Hens, a Preclinical Model of Spontaneous Ovarian Cancer

A Barua, A Yellapa, JM Bahr, MK Adur, CW Utterback… - academia.edu
… in hens are remarkably similar to human OVCA with regard to tumor histopathology and …
Furthermore, methods for the imaging of hen ovaries and ovarian tumors by TVUS scanning …

[HTML][HTML] Current animal model systems for ovarian aging research

H Lu, L Ma, Y Zhang, Y Feng, J Zhang… - Aging and Disease, 2022 - ncbi.nlm.nih.gov
… The D-gal-induced ovarian aging hen model has been … , the histology of the ovary in neonatal
marmosets displays an extremely immature phenotype [125]. Therefore, this animal model

[PDF][PDF] TOXIC EFFECTS OF 2, 3, 7, 8 TETRA-CHLORODIBENZO-P-DIOXIN (TCDD) INDUCED OVARIAN CARCINOMA IN DOMESTIC HENS

MT Al-musawi, AEH Ali, AA Humadi… - Veterinary …, 2020 - researchgate.net
… of experiment also the histopathological changes for left and right ovaries were done at 3 …
hens (Gallus domesticus) is a preclinical model sensitive to epithelial ovarian carcinoma (Lu et …

[HTML][HTML] Comparative transcriptomic study on the ovarian cancer between chicken and human

G Zhu, X Wang, Y Wang, T Huang, X Zhang, J He… - Poultry Science, 2024 - Elsevier
… microRNA profiles of ovarian cancers in hens and updated the … for suitable animal models
for ovarian cancer has garnered … The ovary histology confirmed these hens to be consistent …