… Human Opiorphin, a natural antinociceptive modulator of opioid-dependent pathways. Proc
… Identi cation of human opiorphin, a natural antinociceptive modulator of opioiddependent …

… a physiological modulator of pain perception following injury. … that opiorphin is released
differentially according to the nature … This may reflect the altered pain pathway specific to BMS as …

… This antinociceptive effect was potentiated by administering … sub-effective doses of BK and
opiorphin had a significant anti-… likely role of BK as a modulator of proximal defence reactions, …

… values of opiorphin, a newly defined peptide taking a role in the analgesia pathways, among
… human studies with endogenous opiorphin measurements and external administration of …

… and potentiates intrinsic signaling pathways, which would … allosteric modulator of µ-opioid
receptor, on antinociception by … (MERF IC 50 in the presence of opiorphin was 5.8 nM; IC 50 in …

… both in the modulation of genetic pathways involved in both … dual ectopeptidase inhibitor
with antinociceptive properties. … effect of human opiorphin via opioid-dependent pathways in …

… This study was a pilot evaluation of salivary opiorphin in OSMF. Salivary … Human Opiorphin,
a natural antinociceptive modulator of opioid-dependent pathways. Proceedings of the …

… is highly expressed in the reward pathway and may modulate … directly increase enkephalin
in this pathway, yet it is unknown … Overall, the enkephalinergic system may act as a modulator …

… Abstract: Opiorphin (Oph) is a naturally … Opiorphin (Oph) is a naturally produced short
chain QRFSR-endogenous pentapeptide (H-Gln-Arg-Phe-Ser-Arg-OH) secreted into the human …

… Specifically, their modulation may affect melanocortin four receptor … The levels of the
antinociceptive and inflammatory … Exploring the nature of this relationship might be interesting …