… , affects the microenvironment and the host immune system, and contributes to persistent
infection and pathogenesis. This review summarizes recent findings on the natures and …

… HTLV-1 establish a long-term stealthy viral pathogenesis through a fine-tuned balance of
persistence, immune cell dysfunction, and proliferation of proviral infected cells that collectively …

… , we describe persistent HTLV-1 infection and recent findings on the nature of HTLV-1 gene
… hence HBZ expression, on HTLV-1 persistence and pathogenesis is yet to be investigated. …

Infection with human T-cell leukemia/lymphoma virus type 1 (HTLV-1) has been associated
with various clinical syndromes including co-infection with Strongyloides stercoralis, which is …

… Murine models have significantly contributed to our understanding of HTLV-1 pathogenesis
… Hbz plays a key role in pathogenesis and persistence and, unlike Tax, it is detectible in all …

… -HBZ and inducing the host growth factor production to coordinate the transformation of
infected cells without immortalization secures HTLV-1 persistence for years. Potentiation of HBZ …

… Human T cell leukemia virus type 1 (HTLV-1) is a … that regulate replication and pathogenesis.
Tax (transcriptional … the functions of Tax, thus maintaining a persistent latent infection. …

… apprehended yet, remains a key step to understand HTLV-1 infection and pathogenesis. …
amplification of transformed infected cells without the need of persistent viral production. …

… in the transformation and pathogenesis of HTLV-1 is the multifunctional viral protein Tax.
This … The results of this study raise concerns about the persistence of CRISPR/Cas9-excised …

… Indeed, a persistent NF-κB activity is observed in HTLV-1 transformed … : parasitism and
pathogenesis. Philos Trans R Soc Lond B Biol Sci (2017) 372:20160272. doi: 10.1098/rstb.…