Natural killer cell defects in breast cancer: a key pathway for tumor evasion
E Arianfar, S Shahgordi, A Memarian - International reviews of …, 2021 - Taylor & Francis
… called “non-self recognition”; (c) over-expression of self-proteins in … NK cell activation and
promotes antibody-dependent cell-… could frustrate NK cell antitumor activity in patients with BC. …
promotes antibody-dependent cell-… could frustrate NK cell antitumor activity in patients with BC. …
Killing the invaders: NK cell impact in tumors and anti-tumor therapy
… function and overcome tumor evasion. The characterization … NK self-reactivity and promotes
NK cell activation against … advanced mammary tumors. Furthermore, defective expression of …
NK cell activation against … advanced mammary tumors. Furthermore, defective expression of …
Underlying mechanisms of evasion from NK cells as rationale for improvement of NK cell-based immunotherapies
… breast cancer, chronic lymphocytic leukemia (CLL), ovarian … escape or immune recognition.
Characterization of these … Since NK cell anti-tumor function is frequently impaired in tumor …
Characterization of these … Since NK cell anti-tumor function is frequently impaired in tumor …
Triple-negative breast cancer cells rely on kinase-independent functions of CDK8 to evade NK-cell-mediated tumor surveillance
VM Knab, D Gotthardt, K Klein, R Grausenburger… - Cell Death & …, 2021 - nature.com
… To gain insights into how CDK8 promotes the metastatic potential of murine TNBC, we …
evidence that in addition to T cells, NK cells contribute to the promising antitumor effects of PD-1/…
evidence that in addition to T cells, NK cells contribute to the promising antitumor effects of PD-1/…
Remodeled tumor immune microenvironment (TIME) parade via natural killer cells reprogramming in breast cancer
… NK cells dysfunctional and we shed the light on novel NK cell- directed … In general, immune
evasive mechanisms adapted by BC … system that possess potent antitumor and antimetastatic …
evasive mechanisms adapted by BC … system that possess potent antitumor and antimetastatic …
NK cells-directed therapies target circulating tumor cells and metastasis
… Immune evaded primary tumor cells detached under EMT in … , which they sensitize CTC to
NK cell antitumor effects [41]. In … HER2-positive breast cancer cells are more aggressive and …
NK cell antitumor effects [41]. In … HER2-positive breast cancer cells are more aggressive and …
Mechanisms of apoptosis resistance to NK cell-mediated cytotoxicity in cancer
C Sordo-Bahamonde, S Lorenzo-Herrero… - International journal of …, 2020 - mdpi.com
… cancer cells from diverse solid tumors, such as breast cancer… )-mediated immune suppression,
dampening antitumor NK cell … conditions in tumor evasion of NK cell responses [243,244]. …
dampening antitumor NK cell … conditions in tumor evasion of NK cell responses [243,244]. …
The role of the natural killer (NK) cell modulation in breast cancer incidence and progress
E Razeghian, MC Kameh, S Shafiee, F Khalafi… - Molecular Biology …, 2022 - Springer
… in the induction of breast cancer cells evasion from the cytotoxic … of NK cells combined with
chemotherapy promotes the … and activating markers to enhance NK cell antitumor activity [72]…
chemotherapy promotes the … and activating markers to enhance NK cell antitumor activity [72]…
Overcoming tumor resistance mechanisms in CAR-NK cell therapy
A Valeri, A García-Ortiz, E Castellano… - Frontiers in …, 2022 - frontiersin.org
… surveillance evasion by hematologic tumors. We will also … inhibition increase ex vivo expanded
NK cell antitumor activity … can be enhanced by promoting the interaction of NK cells with …
NK cell antitumor activity … can be enhanced by promoting the interaction of NK cells with …
Natural killer cells in cancer biology and therapy
SY Wu, T Fu, YZ Jiang, ZM Shao - Molecular cancer, 2020 - Springer
… evade CD8 + T cell-mediated cytotoxicity, whereas licensed … use of NK cells as anti-cancer
agents. In addition, unlicensed … for promoting NK cell-induced cytotoxicity toward cancer. As …
agents. In addition, unlicensed … for promoting NK cell-induced cytotoxicity toward cancer. As …