Modeling human trophoblast, the placental epithelium at the maternal fetal interface
M Horii, O Touma, T Bui, MM Parast - Reproduction, 2020 - rep.bioscientifica.com
… the lack of proper modeling systems, the molecular mechanisms of these … models and
tumor-derived trophoblast cell lines, both of which are suboptimal for modeling this unique human …
tumor-derived trophoblast cell lines, both of which are suboptimal for modeling this unique human …
Integrating High-Throughput Approaches and in vitro Human Trophoblast Models to Decipher Mechanisms Underlying Early Human Placenta Development
… While impaired trophoblast differentiation results in pregnancy disorders affecting both
mother and fetus, the molecular mechanisms underlying early human placenta development …
mother and fetus, the molecular mechanisms underlying early human placenta development …
[HTML][HTML] Human placental development and function
T Cindrova-Davies, AN Sferruzzi-Perri - Seminars in cell & developmental …, 2022 - Elsevier
… current knowledge of early human placental development, discuss the critical … models of
trophoblast and endometrial stem cells. In addition, we discuss the role of oxygen in placental …
trophoblast and endometrial stem cells. In addition, we discuss the role of oxygen in placental …
In vitro model of human trophoblast in early placentation
D Bačenková, M Trebuňová, D Čížková, R Hudák… - Biomedicines, 2022 - mdpi.com
… The molecular mechanisms involved in placental formation inside the human body along …
There is a similar molecular mechanism to the expression of some key TFs, including CDX2, …
There is a similar molecular mechanism to the expression of some key TFs, including CDX2, …
Mechanisms of early placental development in mouse and humans
… mouse model and in vitro-derived murine trophoblast stem … into these aspects of placental
development and function, with … to trophoblast differentiation and placenta formation. These …
development and function, with … to trophoblast differentiation and placenta formation. These …
A comprehensive review of human trophoblast fusion models: recent developments and challenges
X Li, ZH Li, YX Wang, TH Liu - Cell Death Discovery, 2023 - nature.com
… and functionality of placental trophoblasts. In this study, we systematically evaluated the …
placental trophoblast fusion models, providing a comprehensive overview of their development …
placental trophoblast fusion models, providing a comprehensive overview of their development …
New era of trophoblast research: integrating morphological and molecular approaches
… development of human placenta is crucial. This review elucidates the uniqueness of the
human placenta in early development from the aspect of structural characteristics and molecular …
human placenta in early development from the aspect of structural characteristics and molecular …
Transcription factor networks in trophoblast development
H Papuchova, PA Latos - Cellular and Molecular Life Sciences, 2022 - Springer
… the three main trophoblast lineages of the human placenta are … stem cells (hTSCs) and
self-organizing trophoblast … to study molecular mechanisms driving trophoblast development and …
self-organizing trophoblast … to study molecular mechanisms driving trophoblast development and …
Early human trophoblast development: from morphology to function
M Gauster, G Moser, S Wernitznig, N Kupper… - Cellular and Molecular …, 2022 - Springer
… The composition of these trophoblast subpopulations is crucial for human placenta development
and alterations are … The key placental cell type involved in all these processes is the …
and alterations are … The key placental cell type involved in all these processes is the …
The TGFβ family in human placental development at the fetal-maternal interface
SM Chuva de Sousa Lopes, MS Alexdottir… - Biomolecules, 2020 - mdpi.com
… that a trophoblast stem cell (TSC) population exists in the early human placenta. However, …
Together with the known sFLT1 and sENG biomarkers of PE, the molecular mechanism is …
Together with the known sFLT1 and sENG biomarkers of PE, the molecular mechanism is …