… in sporadic AD-like pathology and as a potentially valuable … them is Octodon degus (degu),
a South American rodent with … 3 years old) and aged (5 and 6 years old) wild-type captive-…

… age and the appearance of different pathologies. Indeed, … can inhibit the formation of the
amyloid-β peptide (Aβ) aggregates; … SFRP-1 overexpression in an Alzheimer-like mouse model …

… between the Octodon degus and laboratory rodents. First, … relationship with running speed
determine frequency bands (… AD-like pathology spontaneously exhibited by a fraction of aged …

… These animals can present with many pathological changes … Furthermore, there is no evidence
that human-like NFTs are … by inducing the expression of wild-type or mutant human tau in …

… Some pathological aspects associated with Aβ levels in the brain are synaptic dysfunction, …
the retina of animals with Aβ accumulation. We have employed the Octodon degus in which …

… social rodent species Octodon degus (hereafter called degus… the natural aging process to
determine at what point aging … the impact of natural aging or pathological aging (such as AD) …

… in young degus (Octodon degus), a long-lived animal model … play a role in several pathologies
when activated. When present … Aβ release compared to wild-type mice. Although not the …

… diseases, a major type of which is Alzheimer's disease (AD). AD was … The degu (Octodon
degus), a South American rodent, has … Many degus spontaneously develop AD-like pathologies …

… More studies are necessary to determine the relevance of these proteins in normal and
pathological conditions in this animal model or their influence by hormones like estradiol. The …

… , prevent amyloid aggregation in wild-type mice. To deal with this … ; octodon degus, an
animal close to guinea pigs; and dogs (see Table 7). The injection of aluminum maltolate in aged …