… This study identifies transcriptional and functional activities of FZD4-LRP5 agonists. … Norrin
and Wnt signaling in ECs has been studied for its roles in pathological retinal vasculature. For …

… To further assess the retinal toxicity of acriflavine, we examined retinal … that retinal organoids
cultured under hypoxic conditions (1% … that can result from the chronic suppression of 1 or 2 …

… This study demonstrates that NDP gene therapy could be a viable approach to prevent
the progression of hearing loss in a genetic deafblindness syndrome, Norrie disease. The …

… A previous study reported that cell proliferation activity and … myopic retina [26], which made
the retina becomes hypoxic … FDM, the retina was under hypoxia condition and retina glia cells …

… Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied
at single-cell resolution … Hypoxia tolerance in the Norrin-deficient retina and the …

… filter through a monolayer of retinal pigment epithelium (RPE) cells to fuel the retina. Recent
… Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied at …

… fish retina have been found to tolerate prolonged periods of … In this study, we investigated
the effects of hypoxia on … in the fish retina, contributes to their hypoxia tolerance, allowing them …

… The complex pathology of DR is difficult to dissect, given the convoluted cytoarchitecture
of the retina. Here, we performed single-cell RNA sequencing (scRNA-seq) of retina from a …

… of the retina produces chronic hypoxia of inner nuclear-layer (INL… consistent with hypoxia in
Muller glia and retinal neurons, … in Ndp KO retinas with those in the hypoxic cerebral cortex of …

… In this study, we found that 6 h hypoxia treatment significantly decreased GFAP mRNA …
in hypoxic retina may be regulated by both inflammatory mediators from other retinal cells (eg, …