… highlight the potential of HIF-1α … regulatory role of HIF-1 at each step of the metastatic
cascade. Finally, we present the most recent advances in potential pharmacological interventions …

… Illustration of the regulation of hypoxia-inducible factor-1 (HIF-1) stability and transcription
… inhibition, or HIF-1 as a key target, may provide great potential for therapeutic intervention of …

… HIF-1 inhibitors may be promising combinational therapeutic interventions to improve the …
In this review, we briefly introduce the regulation of the HIF-1 pathway and summarize its roles …

… , hypoxia-inducible factor-1 (HIF-1), as an important regulator … process of stroke by regulating
multi-pathways, such as glucose … Resolving when and what interventions for HIF-1 to take …

… for the targeted therapeutic intervention of HIF-1α in cancer. … hypoxia-inducible factor-1
(HIF-1) in the advancement of cancer has been emphasized in this review along with its potential …

… HIF in brain injuries, prospective therapeutic interventions need to differentially target HIF
responses depending on their … Figure 1 presents the factors contributing to the regulation of HIF …

… pathways with inflammation as well as potential therapeutic intervention of the HIF pathway
… hypoxia-dependent mechanisms and regulation of the HIF pathway. Inflammation may alter …

… regulator is lactate dehydrogenase A (LDHA), for its potential to reduce the expression of
HIF-1 … might pave the way for novel therapeutic-intervention strategies to enhance the clinical …

… metabolic processes that are regulated by a hypoxia-inducible factor. In this review… HIF-1
regulation and the Warburg effect in carcinogenesis would unlock new therapeutic interventions…

… of the hypoxia-inducible factors HIF-1α, HIF-2α, and HIF-3α (the latter is not shown as it has
… These proteins dimerize with the constitutively expressed HIF-1β subunit and bind to target …