Three-dimensional Spheroid Culture Combined with Hypoxic Preconditioning Can Promote the Proliferation and Osteogenic Differetiation of BMSCs in Low-oxygen …
X Qiu, Z Feng, G Liu, R Miao, X Tan, J Tao, B Yang… - 2022 - researchsquare.com
… their stemness, and accelerate their proliferation when cultured at … using hypoxic
preconditioning and the formation of BMSCs … differentiation of mesenchymal stem cells and bone …
preconditioning and the formation of BMSCs … differentiation of mesenchymal stem cells and bone …
Dynamic culture of mesenchymal stromal/stem cell spheroids and secretion of paracrine factors
P Fuentes, MJ Torres, R Arancibia… - … in Bioengineering and …, 2022 - frontiersin.org
… of spheroids formed from the number of seeded cells) have … In this work, we defined hypoxia
as a controlled atmosphere … on the biochemical preconditioning of MSC spheroids cultured …
as a controlled atmosphere … on the biochemical preconditioning of MSC spheroids cultured …
Pre-conditioning with IFN-γ and hypoxia enhances the angiogenic potential of iPSC-derived MSC secretome
S Wang, F Umrath, W Cen, AJ Salgado, S Reinert… - Cells, 2022 - mdpi.com
… that the secretome of mesenchymal stromal stem cells (MSCs) … /HA scaffolds, HUVECs
spheroids formed significantly more and … angiogenesis and accelerated tumor growth [52]. Under …
spheroids formed significantly more and … angiogenesis and accelerated tumor growth [52]. Under …
Enhanced viability and function of mesenchymal stromal cell spheroids is mediated via autophagy induction
… This priming supports the MSC activation and accelerates the … such as preconditioning
cells with hypoxia or cytokines, … big-sized spheroids might be more prone to severe hypoxia …
cells with hypoxia or cytokines, … big-sized spheroids might be more prone to severe hypoxia …
Dissecting the effects of preconditioning with inflammatory cytokines and hypoxia on the angiogenic potential of mesenchymal stromal cell (MSC)-derived soluble …
C Gorgun, D Ceresa, R Lesage, F Villa, D Reverberi… - Biomaterials, 2021 - Elsevier
… Interestingly, inflammatory mediators added to hypoxia … related secretome fractions to induce
the formation of tube-like … TNF-α preconditioned MSCs have been described to accelerate …
the formation of tube-like … TNF-α preconditioned MSCs have been described to accelerate …
Hypoxic preconditioning enhances the efficacy of mesenchymal stem cells-derived conditioned medium in switching microglia toward anti-inflammatory polarization in …
H Yu, Z Xu, G Qu, H Wang, L Lin, X Li, X Xie… - Cellular and Molecular …, 2021 - Springer
… from normoxic cultures and from hypoxic cultures. Furthermore, … our results suggested that
hypoxia preconditioning of BMSCs … are bilayer lipid enclosed spheroids with diameter of about …
hypoxia preconditioning of BMSCs … are bilayer lipid enclosed spheroids with diameter of about …
Functional enhancement strategies for immunomodulation of mesenchymal stem cells and their therapeutic application
… differences, and hypoxic preconditioning, a promising tool for … Of note, the simplest method
for 3D culture is a spheroid … of AT-MSCs by accelerating cell cycle synchronization [48]. …
for 3D culture is a spheroid … of AT-MSCs by accelerating cell cycle synchronization [48]. …
Hybrid spheroids containing mesenchymal stem cells promote therapeutic angiogenesis by increasing engraftment of co-transplanted endothelial colony-forming cells …
YC Song, GT Park, HJ Moon, EB Choi, MJ Lim… - Stem Cell Research & …, 2023 - Springer
… Mesenchymal stem cells (MSCs) are multipotent stem cells that can be isolated from … to the
endothelium at sites of hypoxia/ischemia, and participate in new blood vessel formation [14]. It …
endothelium at sites of hypoxia/ischemia, and participate in new blood vessel formation [14]. It …
[HTML][HTML] Functionally enhanced cell spheroids for stem cell therapy: Role of TIMP1 in the survival and therapeutic effectiveness of stem cell spheroids
JK Choi, H Chung, SJ Oh, JW Kim, SH Kim - Acta Biomaterialia, 2023 - Elsevier
… In this paper, we showed that intrinsic hypoxia of spheroids … Recently, stem cell therapy
using mesenchymal stem cells (… in ischemic tissues and accelerate tissue repair through a …
using mesenchymal stem cells (… in ischemic tissues and accelerate tissue repair through a …
[PDF][PDF] Pre-Conditioning with IFN-γ and Hypoxia Enhances the Angiogenic Potential of iPSC-Derived MSC Secretome. Cells 2022, 11, 988
S Wang, F Umrath, W Cen, AJ Salgado… - … Mesenchymal Stem …, 2022 - mdpi.com
… Sprouting assays demonstrated that within Coll/HA scaffolds, HUVECs spheroids formed …
promoted angiogenesis and accelerated tumor growth [52]. Under hypoxic conditions, MSCs …
promoted angiogenesis and accelerated tumor growth [52]. Under hypoxic conditions, MSCs …