… Moreover, studies show that IRF4 is a transcriptional regulator of lipolytic genes in adipose
… IL-21 is a major negative regulator of IRF4-dependent lipolysis affecting Tregs in adipose …

… Finally, we introduce a new subset of Tregs, termed Treg-of-B cells, … Thus, we think that IL-21
exerts a unique function in the … Tregs are also affected by B cells. The suppressive effects of …

… The presence of IFN-y, IL-21, and TLR7 signaling was sufficient to give rise to DN2 B cells
… ) IL-21 is a major negative regulator of IRF4-dependent lipolysis affecting Tregs in adipose …

… Thompson, The impact of adiposity on adipose tissue-resident lymphocyte … Tregs inversely
correlated with macrophages in the AT. Alternatively, the expression of proinflammatory IL-21 …

… ), and the frequency of CD4+ splenocytes producing IL-21, a key factor in balancing the B …
fundamentally essential B cell help and regulation of antibody response to seasonal trivalent …

… are a major stimulus for adipocyte lipolysis, the process that … how exercise and estrogen
affect adipose tissue physiology and … -mediated regulation of adipocyte lipolysis is illustrated by …

… Considering IL-10 can affect both phagocytic uptake and intracellular killing within Mφs,
we set out to clarify this issue. Bacterial … S5 D), known negative regulators of Mφ activation. …