… IL-33 is essential for gut-mediated sensitization and … of IL-33 and TSLP in promoting Th2
responses makes them interesting targets for the treatment of atopic conditions, including food …

… mast cells was abrogated in IL-33 receptor–deficient mice but not … In conclusion, these results
suggest that prophylactic targeting … -induced anaphylaxis, suppression of established food …

… a food allergic mouse model by intraperitoneal sensitization and … show that osthole can
improve food anaphylaxis in mice. The … mast cell degranulation, but also lessen symptoms of food …

… As the major target cells of δ-toxin on the non-tape-stripped skin were likely keratinocytes
in … the epicutaneous sensitization to food allergen, independently of both mast cells and IL-33-…

… or epicutaneous immunotherapies/dietary preventions. p1), 6-8 … IL-33 have all demonstrated
roles during the sensitization … the ability to induce degranulation of the mast cell line LAD2. …

… Because IL-33 and monomeric IgE are also known to promote MC proliferation (42, 53, 60,
61… IL-33 promotes food anaphylaxis in epicutaneously sensitized mice by targeting mast cells. …

… role of IL-33 in epicutaneously sensitized FA found IL-33 to … release of IL-33, which interacts
directly with mast cells through … Targeting the skin to prevent AD or reduce the duration and …

… In addition, IL-4 depletion in epicutaneous sensitized mice … and induces IgE-mediated mast
cell degranulation, although IL-33 … target ST2-expressing cells, including MCs at distant sites. …

… Mechanical skin injury promotes food anaphylaxis by driving intestinal mast cell expansion.
… IL-33 promotes food anaphylaxis in epicutaneously sensitized mice by targeting mast cells. J …

… trials with IL-33 inhibitors are underway in food allergy. We … can promote epicutaneous
sensitization to food allergens and … novel survival factor of dermal mast cells, by interfering with …