Impact of IL28B polymorphism on the response to treatment of hepatitis C with interferon based therapy or direct acting antivirals
S Mohamad, A YOUSRY, AO DALIA… - … Medical Journal of …, 2021 - mjcu.journals.ekb.eg
… Aim of Study: This study aims to correlate IL28B genotype of … genotype was strongly associated
with the success of PEG-… within hepatocytes or other intra-hepatic cells, such as Kupffer …
with the success of PEG-… within hepatocytes or other intra-hepatic cells, such as Kupffer …
The relation between interleukin 28B gene polymorphisms (rs8099917 and rs12980275) and the response of treatment of Hepatitis C Virus genotype 4 patients to …
R Khairy - Microbes and Infectious Diseases, 2021 - journals.ekb.eg
… Also, the IL-28B polymorphism was associated with degree of difference in expression of
intrahepatic interferon-stimulated genes (ISGs) … expression of intrahepatic interferon stimulated …
intrahepatic interferon-stimulated genes (ISGs) … expression of intrahepatic interferon stimulated …
[HTML][HTML] Functional genetic variants of the IFN-λ3 (IL28B) gene and transcription factor interactions on its promoter
S Roy, DG Roy, A Bhushan, S Bharatiya… - Cytokine, 2021 - Elsevier
… be entirely explained by IFN-λ4, implying that other mechanisms related to rs8099917 and
… Therefore, to test the effect of both the SNPs on gene expression, we cloned the IFN-λ3 3′…
… Therefore, to test the effect of both the SNPs on gene expression, we cloned the IFN-λ3 3′…
[HTML][HTML] Interleukin 28B Polymorphism as a Predictor of Sustained Virological Response to Sofosbuvir-Based Therapy for Hepatitis C Virus Patients
… the genotype and allele frequency distributions of IL28B (… the non–CC IL28B genotype has
been strongly associated with … (98%) with the CC genotype of IL28B, compared to 202 out of …
been strongly associated with … (98%) with the CC genotype of IL28B, compared to 202 out of …
The presence of interferon affects the progression of non-alcoholic fatty liver disease
M Møhlenberg, PL Eriksen, TL Laursen, MB Nielsen… - Genes & …, 2022 - nature.com
… test was used to compare the interferon stimulated gene (ISG)-… , the blood parameters, tissue
gene expression and the histology … in both circulating and intrahepatic immune cells in HCV-…
gene expression and the histology … in both circulating and intrahepatic immune cells in HCV-…
Defining the key intrahepatic gene networks in HCV infection driven by sex
E Marchi, N Ramamurthy, MA Ansari, CE Harrer… - Gut, 2023 - gut.bmj.com
… of cirrhosis and the role of IL28B genotype, we find a strong … with the module enriched with
interferon stimulated genes (ISGs) (… as dimension gene expression in interferon module and …
interferon stimulated genes (ISGs) (… as dimension gene expression in interferon module and …
Recipient IL28B genotype CT is a predictor of new onset diabetes mellitus in liver transplant patients with chronic hepatitis C
UM Al-Jarhi, S Mogawer, M Mohsen… - International Journal of …, 2021 - Springer
… IL28B polymorphism is significantly associated with new onset diabetes after LDLT. CT …
The aim of this work was to investigate the association of IL28B genotype with the occurrence of …
The aim of this work was to investigate the association of IL28B genotype with the occurrence of …
Association of Interleukin 28B Polymorphism with Clearance of Hepatitis C Virus: A Mini Review
M Shaheen, S Afzal, B Khubaib, I Amin… - … Gene Expression, 2020 - dl.begellhouse.com
… We find that IL28B variants rs8099917 and rs12979860 strongly influence results of … or CT
genotypes. These SNPs are associated with expression of intrahepatic IFN-stimulated genes …
genotypes. These SNPs are associated with expression of intrahepatic IFN-stimulated genes …
Genetic polymorphism in IL-28 B and LMP-7 genes: Role in HCV-induced Hepatocellular Carcinoma
NS Elmekawy, ST Mohamed… - Egyptian Journal of …, 2022 - ejmm.journals.ekb.eg
… of IFN-related cytokines that exhibits similar biologic characteristics with type I IFNs. The
IFNstimulated … Individuals with the genotype IL28B TT had a significantly higher risk of HCC …
IFNstimulated … Individuals with the genotype IL28B TT had a significantly higher risk of HCC …
[HTML][HTML] Interferon response in hepatitis C virus-infected hepatocytes: issues to consider in the era of direct-acting antivirals
… -dependent gene expression was delayed after stimulation with … Excessive IFN stimulation
is prevented through the close … infer that maintaining intrahepatic type I IFN signaling at the …
is prevented through the close … infer that maintaining intrahepatic type I IFN signaling at the …