Combined and distinct roles of Agr proteins in Clostridioides difficile 630 sporulation, motility, and toxin production
UKB Ahmed, TM Shadid, JL Larabee, JD Ballard - MBio, 2020 - Am Soc Microbiol
… difficile senses growth conditions to regulate toxin expression and … Agr1, the focus of our
study, is a two-gene locus encoding … factors might be impacted by intracellular AgrD1, we were …
study, is a two-gene locus encoding … factors might be impacted by intracellular AgrD1, we were …
Good gone bad: one toxin away from disease for Bacteroides fragilis
E Valguarnera, JB Wardenburg - Journal of molecular biology, 2020 - Elsevier
… the active C-terminal domain into the extracellular milieu [74,75]. … Studies on the genetic
locus that encodes BFT have been … controls transcription [94]. A key mechanism for control of …
locus that encodes BFT have been … controls transcription [94]. A key mechanism for control of …
Pathogenicity and virulence of Clostridium perfringens
I Mehdizadeh Gohari, M A. Navarro, J Li, A Shrestha… - Virulence, 2021 - Taylor & Francis
… perfringens toxins is highly regulated via processes involving … of toxins and extracellular
degradative enzymes produced by … loci on large tcp-conjugative plasmids suggests that the toxin …
degradative enzymes produced by … loci on large tcp-conjugative plasmids suggests that the toxin …
The extracellular contractile injection system is enriched in environmental microbes and associates with numerous toxins
AM Geller, I Pollin, D Zlotkin, A Danov… - Nature …, 2021 - nature.com
… we identify eCIS loci in 1,249 bacterial and archaeal genomes and reveal an enrichment of
these loci … , Tse2 50 , as a positive control, and two negative controls: a monomeric enhanced …
these loci … , Tse2 50 , as a positive control, and two negative controls: a monomeric enhanced …
Identification of genetic factors influencing metabolic dysregulation and retinal support for MacTel, a retinal disorder
… We aimed to: (1) confirm the originally reported genetic loci, and assess the strength of …
genotype data from that study and identified as heterozygotes two healthy controls and seven age…
genotype data from that study and identified as heterozygotes two healthy controls and seven age…
Staphylococcal biofilm development: structure, regulation, and treatment strategies
K Schilcher, AR Horswill - Microbiology and Molecular Biology …, 2020 - Am Soc Microbiol
… the production of extracellular toxins and enzymes (244… that Rot can potentially regulate all
four protease loci, but the degree … The idea is to identify molecules that specifically target the …
four protease loci, but the degree … The idea is to identify molecules that specifically target the …
In vitro and in vivo biofilm forming Vibrio spp: a significant threat in aquaculture
M Arunkumar, F LewisOscar, N Thajuddin… - Process …, 2020 - Elsevier
… with the self-production of extracellular polysaccharides (EPS). … aquaculture have been
identified, analyzed and documented … vulnificus, wcr locus regulates the EPS production and the …
identified, analyzed and documented … vulnificus, wcr locus regulates the EPS production and the …
Biological functions of type II toxin-antitoxin systems in bacteria
M Kamruzzaman, AY Wu, JR Iredell - Microorganisms, 2021 - mdpi.com
… biofilm production presumably by releasing extracellular DNA (… prophage but also regulates
the production of active phage … Later, the hipAB locus was identified as a TA system [133,134…
the production of active phage … Later, the hipAB locus was identified as a TA system [133,134…
Pathogenicity assessment of Shiga toxin-producing Escherichia coli strains isolated from wild birds in a major agricultural region in California
MQ Carter, B Quiñones, N Laniohan… - Frontiers in …, 2023 - frontiersin.org
… mobile genetic elements (MGEs), including prophages for Shiga toxin expression, the locus
of … % amino acids sequence identity while the Pic encoded by the second plasmid (locus tag: …
of … % amino acids sequence identity while the Pic encoded by the second plasmid (locus tag: …
Identifying a molecular mechanism that imparts species-specific toxicity to YoeB toxins
JR Ames, J McGillick, T Murphy, E Reddem… - Frontiers in …, 2020 - frontiersin.org
… chimera gains toxicity to Ec cells and lessens toxicity to At cells. … helix sequence is less toxic
to Ec and gains toxicity to At cultures. … , and thus controls growth inhibition and YoeB toxicity. …
to Ec and gains toxicity to At cultures. … , and thus controls growth inhibition and YoeB toxicity. …