… be present in the majority of bacterial chromosome origins. Moreover, we find … basal unwinding
system’ (BUS). In this study we investigated whether the oriC unwinding system identified …

… bacteria, replication of the chromosome starts with the assembly of the replisome at the
origin … of the DnaA-trio are part of the basal unwinding system (ie, required for DnaA-dependent …

… a chromosome origin are loaded around ssDNA. Bacterial chromosome origin unwinding
to … Therefore, the model described here would apply to all putative BUS systems identified. …

… boxes and an AT-rich DNA unwinding element (DUE), that serve … DnaA binds to these
sequences, triggering the unwinding of … In our aim to identify the sequence(s) responsible for …

… encode information that promotes specific unwinding of the … the identification of conserved
chromosome origin sequence … bacterial chromosome origin Basal Unwinding System (BUS, …

… , termed orisomes, unwind replication origin (oriC) DNA and … We identify three known
transcriptional modulators, SeqA, … all growth rates, bacterial chromosome replication begins once…

… maintain its structural integrity and identity under the changing … constrain DNA unwinding,
in the form of either untwisting or … of genes on bacterial chromosomes. Nucleic Acids Res 37:…

… coli appears to be an opportunistic pathogen, based on the basal … This coiling allows unwinding
of duplex DNA by relieving … de ine the complexities of bacterial chromosome duplication. …

… mains of GPCRs and identified their mechanism of formation … We studied basal, or
ligand-independent, signaling because … In this paper, I review present ideas about the origin of …

… feature of processive DNA unwinding enzymes. The … In the absence of DNA, purified Bad
displayed a basal ATPase … In this work, we identified and characterised a bacterial helicase–…