… class of gram-negative OMPs whose transport and insertion into the OM is widely-conserved,
largely self… The increased signaling we observe could also be due to intracellular detection …

… , tendency for self-association, or off-target autoreactivity are … in disruption of receptor–ligand
interaction (ie, interaction of a … where there is a well-identified, and preferably invariable, …

… identified so far do not respond to the same microbial antigens as MAIT cells, are self-reactive …
the plasma membrane and present self-antigens or microbial ligands acquired in the ER …

… MR1 is a non-polymorphic MHC class I–like molecule that … in the absence of microbial ligands.
Purified, circulating Vα7.2 + T … whether self-reactive MAIT cells could also be identified ex …

… our understanding of AD by identifying potential targets for … potential pathogen-derived
peptide ligands for the 1E6 TCR … protein databases from pathogenic bacteria and fungi and by …

… undergo point mutations to escape detection like peptide, the … Examples of pan-CD1 ligands
that bind multiple human CD1 … of more potent SM blockers that can reduce the autoreactive …

… Thus, during autoimmunity, T cells bearing self-reactive TCRs … , these microbial antigens
function as self-ligands to promote … also identified TGFβ3 as a potent cytokine that drives high …

… presents microbial ligands from bacteria colonizing the skin is unclear. Here we identified …
testing with a CD1a-autoreactive T cell line originally isolated from human skin (DermT) 17,…

… to bind distinct ligands likely accounts for the recent identification of … reactive to alternative
sets of microbial or self MR1 ligands. … In conclusion, self-reactive MR1T cells, seem to be a …

… cationic intrinsically disordered antimicrobial peptides (CIDAMPs), … allows the identification
of antigen epitopes from microbes, … A high percentage of antigenic peptides identified in this …