[HTML][HTML] Weighted gene coexpression network analysis reveals essential genes and pathways in bipolar disorder

ZQ Zhang, WW Wu, JD Chen, GY Zhang, JY Lin… - Frontiers in …, 2021 - frontiersin.org
… This study aimed to identify the essential pathways and genes involved in BD using
weighted gene … their functional pathways and potential hub genes. Using two available BD …

[HTML][HTML] Exploring hub genes and crucial pathways linked to oxidative stress in bipolar disorder depressive episodes through bioinformatics analysis

S Wu, H Hu, Y Li, Y Ren - Frontiers in Psychiatry, 2024 - frontiersin.org
… relationship between BD and OS by identifying key hub genes implicated in OS pathways. …
Our approach encompassed differential expression analysis, weighted gene co-expression …

Weighted gene coexpression network analysis identifies specific modules and hub genes related to major depression

G Zhang, S Xu, Z Yuan, L Shen - Neuropsychiatric Disease and …, 2020 - Taylor & Francis
… innate immune system linked to depression in human and rodent studies. As such, it was
important to identify the critical genes and key-related pathways that may be related to innate …

[HTML][HTML] Genetic pathways and functional subnetworks for the complex nature of bipolar disorder in genome-wide association study

CY Kuo, TY Chen, PH Kao, W Huang… - Frontiers in Molecular …, 2021 - frontiersin.org
… informative genes identified from enriched pathways, we … a pathway-based analysis using
weighted competitive and self-… and 39 interactions, with a hub in transcription factor SP1 with …

Novel loci and potential mechanisms of major depressive disorder, bipolar disorder, and schizophrenia

H Wang, Z Yi, T Shi - Science China Life Sciences, 2022 - Springer
… of MTAG weight factors for each disease increased 1.214fold, … 101 genes showed that FURIN
was one of the top hub proteins. … Identification of shared risk loci and pathways for bipolar

[HTML][HTML] Integrative network analysis identifies differential regulation of neuroimmune system in Schizophrenia and Bipolar disorder

A Sahu, HA Chowdhury, M Gaikwad… - Brain, behavior, & …, 2020 - Elsevier
Weighted gene correlation networks were constructed to find non-preserved (NP) modules
identified the overlapping and unique set of genes, components of core and specific pathway

[HTML][HTML] Identification of key modules and genes associated with major depressive disorder in adolescents

B Zhao, Q Fan, J Liu, A Yin, P Wang, W Zhang - Genes, 2022 - mdpi.com
… B cell receptor signaling pathways associated with depression using the … a gene-weighted
co-expression network to detect key gene modules and hub genes which were highly related

Identification of Key Genes and Biological Pathways in Bipolar Disorder by Bioinformatics and Next Generation Sequencing Data Analysis

B Vastrad, C Vastrad - bioRxiv, 2022 - biorxiv.org
Bipolar disorder (BD), also known as psychiatric disorder, affects millions of people all over
the world. The aim of this investigation was to screen and verify hub genes involved in BD as …

Analysis of topological properties and drug discovery for bipolar disorder and associated diseases: A bioinformatics approach

KA Shadhin, MR Hasan, BK Paul, K Ahmed… - Cellular and Molecular …, 2020 - cellmolbiol.org
Genes are sorted by their weight in ascending order. The numerical values of the identified
responsible genes … the common genes and the common gene regulatory pathway between …

[HTML][HTML] Integrative analysis to identify shared mechanisms between schizophrenia and bipolar disorder and their comorbidities

VS Bharadhwaj, S Mubeen, A Sargsyan… - Progress in Neuro …, 2023 - Elsevier
… at the gene-level and compare our findings against disease-… to identify disease-specific
as well as common pathways. … enriched pathways across datasets and disorders to identify