Characterization of the human immunodeficiency virus (HIV-1) envelope glycoprotein conformational states on infectious virus particles

HT Nguyen, Q Wang, S Anang, JG Sodroski - Journal of Virology, 2023 - Am Soc Microbiol
… We identify requirements to keep the relevant envelopeHuman immunodeficiency virus type
1 (HIV-1) entry into … However, we found that even with intact vpu and nef genes on the IMC, …

[HTML][HTML] … , biochemical profiles and molecular detection of envelope gene (gp-41) in human immunodeficiency virus (HIV) among newly diagnosed patients

A Anjum, A Rehman, H Siddique, AA Rabaan… - Medicina, 2022 - mdpi.com
envelope gene (GP41) was determined by using PCR. Four primers were used for the detection
of glycoprotein GP41 as shown in Table 1… by recombination in the envelope region. This …

[HTML][HTML] Zikavirus prME Envelope Pseudotyped Human Immunodeficiency Virus Type-1 as a Novel Tool for Glioblastoma-Directed Virotherapy

M Kretschmer, P Kadlubowska, D Hoffmann… - Cancers, 2020 - mdpi.com
… ), have been identified as the cell … virus and tumor genetics has improved as a result of
improved molecular biology, leading to the generation of recombinant, genetically modified virus

[HTML][HTML] HIV-1 unique recombinant forms identified in Slovenia and their characterization by near full-length genome sequencing

MM Lunar, J Mlakar, TM Zorec, M Poljak - Viruses, 2020 - mdpi.com
… , human immunodeficiency virus (HIV) remains one of the major global disease burdens,
causing 770,000 deaths in 2018 [1]. … by the remarkable global genetic diversity, reflected in the …

Dual pathways of human immunodeficiency virus type 1 envelope glycoprotein trafficking modulate the selective exclusion of uncleaved oligomers from virions

S Zhang, HT Nguyen, H Ding, J Wang, S Zou… - Journal of …, 2021 - Am Soc Microbiol
… To identify potential cell and virion sources of state-1 Envs, we studied Env expression, …
mRNA comprising HIV-1 AD8 rev and env and two selectable marker genes (puromycin-T2A-…

Development of human immunodeficiency virus type 1 resistance to 4′-ethynyl-2-fluoro-2′-deoxyadenosine starting with wild-type or nucleoside reverse …

ME Cilento, AB Reeve, E Michailidis… - Antimicrobial Agents …, 2021 - Am Soc Microbiol
… Using recombinant viruses, we validated the role for M184V … We identified a double-mutant
virus with a moderate level of … V184 and S114 impinge into the substrate envelope of the 4′-…

[HTML][HTML] Gene editing in CHO cells to prevent proteolysis and enhance glycosylation: Production of HIV envelope proteins as vaccine immunogens

SW Li, M Wright, JF Healey, JM Hutchinson… - … One, 2020 - journals.plos.org
… based on recombinant envelope (Env) glycoproteins have been advanced into human clinical
… Here, we describe the identity of another protease (C1s) that results in the degradation of …

[HTML][HTML] Antisense transcripts and antisense protein: a new perspective on human immunodeficiency virus type 1

J Savoret, JM Mesnard, A Gross, N Chazal - Frontiers in Microbiology, 2021 - frontiersin.org
… years later describing the detection of HIV-1 antisense transcripts, … Immunodeficiency Virus
(FIV) envelope gene was also … recombinant forms (CRFs) of HIV-1 (sequences were retrieved …

Multiple recombinant events in human T-cell Leukemia virus Type 1: complete sequences of recombinant African strains

O Cassar, A Desrames, A Marçais, O Gout… - Emerging microbes & …, 2020 - Taylor & Francis
… designed to amplify 885-bp-long fragment of the envelope gene. … Recombination between
a-WA and a-Sen strain is identified because there is just enough genetic diversity between

[HTML][HTML] Evaluation of novel HIV vaccine candidates using recombinant vesicular stomatitis virus vector produced in serum-free Vero cell cultures

M Mangion, JF Gélinas, ABZ Gashti, H Azizi… - Vaccine, 2020 - Elsevier
… system caused by Human Immunodeficiency Virus (HIV) … More specially, a chimeric HIV-1
envelope composed of a … -based HIV vaccine candidates, identified the growth conditions and …