… Total NNN exposures to the rats from the 50, 100, or 500 ppm groups over … adduct level in
rat liver and lung. N 6 -HPB-dAdo is a new and structurally unique type of DNA adduct formed …

… unique dGuo adduct formed by NNKOAc has been identified … DNA phosphate adducts were
quantified using the same rat … of 107 structurally unique PHB DNA phosphate adducts 76 (…

… , on the DNA structure by analyzing DNA adduct profiles. This … By identifying the DNA adducts
formed due to carcinogen … statistically significant DNA adducts within three distinct groups: …

… adduct panel formed by NNN 5′-hydroxylation and identify … study characterized a structurally
unique dAdo adduct N 6 -… investigating new DNA phosphate adducts formed by NNN 5′-…

… We have identified a new class of DNA adducts, DNA–RNA … to the formation of spontaneous
tumors, for instance in rats, the … Here, we have identified and structurally characterized, for …

… DNA adducts together with the technique used for identification… One unique entry was
associated to each DNA adduct and … ) a lack of structural characterization of the DNA adduct, 2) no …

… the detection of 40 DNA adducts in vitro and 20 DNA adducts … adducts by using the shared
structural characteristics of DNA … and detected in vitro and in rats exposed to CPA or its …

… identify gene regions susceptible to DNA adduct formation. … been shown for DNA-phosphate
adducts formed by the … of site-specific effects of DNA adducts on DNA structure and function, …

… N-nitrosodiethylamine on more than 4000 rats established a … carcinogens which are virtually
unique to tobacco products and … This study thus identified (S)-NNN as the only powerful oral …

… DNA damage while the major role played by DNA phosphate … from rat models upon CF
exposure, we have identified several … cycle activation, the adducts could cause an uncontrolled …