Identification of miRNA-mediated subpathways as prostate cancer biomarkers based on topological inference in a machine learning process using integrated gene …

Z Ning, S Yu, Y Zhao, X Sun, H Wu, X Yu - Frontiers in Genetics, 2021 - frontiersin.org
… To identify the precise local subpathway regions associated with prostate cancer, we obtained
reliable miRNA–target gene pairs … to the “TGF-beta signaling pathway” (hsa04350), which …

MiRNA-Mediated Subpathway Identification and Network Module Analysis to Reveal Prognostic Markers in Human Pancreatic Cancer

Y Liu, Y Cui, X Bai, C Feng, M Li, X Han, B Ai… - Frontiers in …, 2020 - frontiersin.org
paired miRNA/mRNA expression data. They subsequently … PC-relevant subpathways
identified by integrating DE genes, … each miRNA-mRNA module and PC-relevant subpathways

Identification of miRNA-mRNA associations in hepatocellular carcinoma using hierarchical integrative model

RS Varghese, Y Zhou, M Barefoot, Y Chen… - BMC medical …, 2020 - Springer
… The purpose of this paper is to integrate miRNA-seq and … Sirtuin signaling was one of the
top pathways identified from … Some of the miRNA-mRNA pairs identified in this study are …

Integrated transcriptomic analysis of the miRNAmRNA interaction network in thin endometrium

L Zong, S Zheng, Y Meng, W Tang, D Li, Z Wang… - Frontiers in …, 2021 - frontiersin.org
… were used to analyze the miRNAmRNA pairs, which were … study identified several
DEGs-related signaling pathways by … of the miRNA-mediated changes in mRNA expression in thin …

Integrative in silico approaches to analyse microRNA‐mediated responses in human diseases

M Agrawal, A Mani - The Journal of Gene Medicine, 2024 - Wiley Online Library
… This review explains how to apply the existing methods to analyse miRNA-mediated
integrate gene expression profiles datasets, protein–protein interaction and miRNAmRNA

miRNA and mRNA Signatures in Human Acute Kidney Injury Tissue

D Janosevic, T De Luca, RM Ferreira, DL Gisch… - The American Journal of …, 2024 - Elsevier
… AKI, then integrated analyses of miRNA-mRNA interactions and associated pathways.
Groups of … in the data that inversely correlated with genes, which may implicate miRNA-mediated

Survival Marker miRNA-Mediated Subpathways of Breast Invasive Carcinoma Derived From Activity Profile

Z Ning, S Yu, Y Zhao, Y Wang, Q Fan, T Song… - IEEE Access, 2020 - ieeexplore.ieee.org
miRNA-mediated subpathways toward precise identification of … pairs from TarBase, and 750
381 pairs from miRTarBase. We … Børresen-Dale, ‘‘MiRNA-mRNA integrated analysis reveals …

Disruption of miRNA-mRNA networks defines novel molecular signatures for penile carcinogenesis

TK Furuya, CB Murta, AG Murillo Carrasco, M Uno… - Cancers, 2021 - mdpi.com
… profiles to identify molecular drivers and pathways involved in … To integrate our data of
miRNA and mRNA expression … of miRNA-mRNA pairs in PeC showing that eight pairs changed …

Multi-omics network characterization reveals novel microRNA biomarkers and mechanisms for diagnosis and subtyping of kidney transplant rejection

Y Lin, L Wang, W Ge, Y Hui, Z Zhou, L Hu… - Journal of Translational …, 2021 - Springer
… -related genes, immune signaling pathways and identified miRNAs, … integration of DE-miRNA/mRNA,
miRNA-mRNA and PPI data for systems-level characterization of miRNA-mediated

Integrative network analysis of miRNA-mRNA expression profiles during epileptogenesis in rats reveals therapeutic targets after emergence of first spontaneous …

N Khemka, G Morris, L Kazemzadeh, LS Costard… - Scientific Reports, 2024 - nature.com
… Here, we integrated miRNA and mRNA expression profiles … binding interactions, for instance
through miRNA-mediated … and can confound identification of the critical molecular pathways