Assessing the severity of traumatic brain injury—time for a change?

O Tenovuo, R Diaz-Arrastia, LE Goldstein… - Journal of clinical …, 2021 - mdpi.com
Traumatic brain injuries (TBIs) are among the most common maladies affecting humanity.
Grading injury severity is an early step in management and is a first step towards prognosis …

Advanced neuroimaging role in traumatic brain injury: a narrative review

L Hu, S Yang, B Jin, C Wang - Frontiers in Neuroscience, 2022 - frontiersin.org
… Perfusion Weighted Imaging Traumatic brain injury is related to impaired cerebral vascular
auto-regulation function, vascular injury and increased blood-brain barrier permeability, then …

The role of blood biomarkers for magnetic resonance imaging diagnosis of traumatic brain injury

JK Yue, PS Upadhyayula, LN Avalos, H Deng… - Medicina, 2020 - mdpi.com
… Studies were included if they studied an adult population (age > 18), studied a patient
population with traumatic brain injury, studied a serum biomarker and had patients who had MRI …

Assessment of brain injury using portable, low-field magnetic resonance imaging at the bedside of critically ill patients

KN Sheth, MH Mazurek, MM Yuen, BA Cahn… - JAMA …, 2021 - jamanetwork.com
… Importance Neuroimaging is a key step in the clinical evaluation of brain injury. Conventional
magnetic resonance imaging (MRI) systems operate at high-strength magnetic fields (1.5-3 …

Detecting axonal injury in individual patients after traumatic brain injury

AE Jolly, M Bălăeţ, A Azor, D Friedland, S Sandrone… - Brain, 2021 - academic.oup.com
… axonal injury at the individual level have not yet been developed. Here, we present a pipeline
for diffusion imaging analysis designed to accurately assess the presence of axonal injury

Diffuse axonal injury predicts neurodegeneration after moderate–severe traumatic brain injury

NSN Graham, A Jolly, K Zimmerman, NJ Bourke… - Brain, 2020 - academic.oup.com
… diffuse axonal injury predicts the degree of progressive post-traumatic … after moderate–severe
traumatic brain injury and 19 healthy … tensor imaging as a measure of diffuse axonal injury. …

Blood biomarkers on admission in acute traumatic brain injury: relations to severity, CT findings and care path in the CENTER-TBI study

E Czeiter, K Amrein, BY Gravesteijn, F Lecky… - …, 2020 - thelancet.com
… Serum biomarkers may inform and improve care in traumatic brain injury (TBI). We aimed to
correlate serum biomarkers with clinical severity, care path and imaging abnormalities in TBI…

Improving diagnosis and prognosis in acute severe brain injury: a multimodal imaging protocol

K Kazazian, L Norton, G Laforge, A Abdalmalak… - Frontiers in …, 2021 - frontiersin.org
… Written informed consent will be obtained by the next of kin, as the patient population of
this study will be unable to consent for acute imaging procedures. Patients will be asked to …

Magnetic resonance imaging biomarkers of brain connectivity in predicting outcome after mild traumatic brain injury: a systematic review

J Puig, MJ Ellis, J Kornelsen, TD Figley… - Journal of …, 2020 - liebertpub.com
… tensor imaging (DTI) to aid in the diagnosis and management of patients with mild traumatic
brain injury (mTBI). To determine whether early MRI biomarkers of brain connectivity are …

S100B, GFAP, UCH-L1 and NSE as predictors of abnormalities on CT imaging following mild traumatic brain injury: a systematic review and meta-analysis of …

M Amoo, J Henry, PJ O'Halloran, P Brennan… - Neurosurgical …, 2022 - Springer
… mild traumatic brain injury (mTBI). As such, we aimed to characterise their accuracy at
various thresholds. MEDLINE, SCOPUS and EMBASE were searched, and articles reporting the …