An update on the immune landscape in lung and head and neck cancers

JW Carlisle, CE Steuer, TK Owonikoko… - CA: a cancer journal …, 2020 - Wiley Online Library
alterations in the epidermal growth factor receptor (EGFR) or anaplastic lymphoma kinase
(ALK) genes were randomized to receive either pembrolizumab … are not optimal candidates for …

[HTML][HTML] Immunotherapy for head and neck cancer: a paradigm shift from induction chemotherapy to neoadjuvant immunotherapy

H Shibata, S Saito, R Uppaluri - Frontiers in Oncology, 2021 - frontiersin.org
immunotherapy has the potential to enhance clinical outcomes by increasing anti-tumor
immune responses in the presence of abundant tumor-… of histologic changes is understood. …

Biomarkers for immunotherapy response in head and neck cancer

N Gavrielatou, S Doumas, P Economopoulou… - Cancer treatment …, 2020 - Elsevier
… to the seven steps of Cancer-Immunity Cycle as proposed by … such as HPV, genetic alterations,
neoantigens and smoking … and neck tumours making the former better candidates for IO. …

Immunomodulatory therapy in head and neck squamous cell carcinoma: recent advances and clinical prospects

A Khadela, Y Shah, P Mistry… - Technology in Cancer …, 2023 - journals.sagepub.com
… of head and neck cancer. Over the last decade, the emergence of … tumor immunotherapy
is premised on the principle that immune escape is attainable because of changes in immune

[HTML][HTML] The role of T-cells in head and neck squamous cell carcinoma: from immunity to immunotherapy

MPS Damasio, CS Nascimento, LM Andrade… - … in oncology, 2022 - frontiersin.org
… The intricate mechanism involved in the immunity of head and neck cancers has … The
study reports differences in immunological potency attributable to alteration of polymer and the …

[HTML][HTML] Defining the role of immunotherapy in the curative treatment of locoregionally advanced head and neck cancer: promises, challenges, and opportunities

R Saddawi-Konefka, AB Simon, W Sumner… - … in Oncology, 2021 - frontiersin.org
… of tumor-immune evasion and immunotherapeutic resistance. … infiltrate and a response to
immunotherapy similar to that … dynamic changes occurring downstream from selective immune

Opportunities and challenges in combining immunotherapy and radiotherapy in head and neck cancers

KCW Wong, D Johnson, EP Hui, RCT Lam… - Cancer Treatment …, 2022 - Elsevier
… effects, and various immune checkpoint inhibitors (ICIs) have … the unique immune landscapes
of virus-induced cancers, … or depletion of T cells or changes in the TME after RT which …

[HTML][HTML] Head and neck squamous cell carcinoma: risk factors, molecular alterations, immunology and peptide vaccines

Z Sun, X Sun, Z Chen, J Du, Y Wu - International Journal of Peptide …, 2022 - Springer
… To establish effective immunotherapies, a greater … molecular alterations in HNSCC, explore
the immune response to … 5-year survival rates of head and neck cancer throughout the world …

[HTML][HTML] Immunotherapy in head and neck cancer when, how, and why?

D Pereira, D Martins, F Mendes - Biomedicines, 2022 - mdpi.com
… This review aims to explore immunotherapy (immune checkpoint inhibitors (ICI), therapeutic
… and the host immune system, where modifications in immunological surveillance and the …

Immunotherapy in head and neck cancer: where do we stand?

NG Vallianou, A Evangelopoulos, D Kounatidis… - Current Oncology …, 2023 - Springer
… of newer immune-checkpoint inhibitors; the use of tumor vaccines … novel immunotherapeutic
agents that are candidates for … of response to immunotherapy, reflecting modifications of the …