Protection against a chlamydial respiratory challenge by a chimeric vaccine formulated with the Chlamydia muridarum major outer membrane protein variable domains using the …

DF Tifrea, S Pal, J Fairman, P Massari, LM de La Maza - npj Vaccines, 2020 - nature.com
Chlamydia trachomatis is the most frequently detected sexually … The Chlamydia major outer
membrane protein (MOMP) is the … acid sequence (with peptide 25 overlapping the N and C

Vaccination with the recombinant major outer membrane protein elicits long-term protection in mice against vaginal shedding and infertility following a Chlamydia …

S Pal, MI Cruz-Fisher, C Cheng, JR Carmichael… - NPJ vaccines, 2020 - nature.com
Chlamydia trachomatis infections. The aim of this study was to determine the ability of a vaccine
formulated with the recombinant major outer membrane protein (… using MOMP peptides. …

Chlamydia: what is on the outside does matter

A Gitsels, S Van Lent, N Sanders… - Critical reviews in …, 2020 - Taylor & Francis
Chlamydia trachomatis can synthesise the prokaryotic lipids … The major outer membrane
protein is a 39 500 Da protein, … and their apparent immunoaccessibility/antigenicity suggests …

Improved protection against Chlamydia muridarum using the native major outer membrane protein trapped in Resiquimod-carrying amphipols and effects in protection …

DF Tifrea, S Pal, C Le Bon, MJ Cocco, M Zoonens… - Vaccine, 2020 - Elsevier
Chlamydia trachomatis is the most common bacterial sexually transmitted pathogen … to
25-mer peptides corresponding to the C. muridarum mature MOMP were analyzed by ELISA. …

… Membrane Protein G Has a Neutral Effect and the Plasmid Glycoprotein 3 an Antagonistic Effect on the Ability of the Major Outer Membrane Protein to Elicit Protective …

A Slepenkin, S Pal, S Hoang-Phou… - Vaccines, 2023 - mdpi.com
Chlamydia trachomatis is the most common bacterial sexually … peptides corresponding to
the entire amino acid sequence of … Peptide 25 overlapped the N-terminus and C-terminus of …

Induction of protection in mice against a respiratory challenge by a vaccine formulated with exosomes isolated from Chlamydia muridarum infected cells

S Pal, Y Mirzakhanyan, P Gershon, DF Tifrea… - NPJ vaccines, 2020 - nature.com
… the major outer membrane protein and the polymorphic … Chlamydia trachomatis is the most
common sexually … of each protein based on the three most abundant tryptic peptide species …

… and CpG-1018+ Montanide ISA 720 VG, for Safety and for Their Ability to Elicit Protective Immune Responses in Mice against a Respiratory Challenge with Chlamydia …

S Pal, A Slepenkin, J Felgner, D Huw Davies… - Pathogens, 2023 - mdpi.com
… for Chlamydia trachomatis infections. Here, using the Chlamydia muridarum major outer
membrane protein (MOMP… Their reactivity to 25-aa overlapping peptides corresponding to the C. …

A primary Chlamydia trachomatis genital infection of rhesus macaques identifies new immunodominant B-cell antigens

A Randall, A Teng, X Liang, S Pal, AF Tarantal, J Fike… - PloS one, 2021 - journals.plos.org
… critical for the biosynthesis of the outer membrane [51]. CT242 … that antibodies to linear
peptides were generated [61, 62]. … Increased immunoaccessibility of MOMP epitopes in a vaccine …

Determination of the safety and efficacy of recombinant Chlamydia muridarum MOMP vaccines, formulated with CpG-1826 and 70%, 50%, 30% or 10% concentrations …

L de la Maza, A Slepenkin, S Pal, A Rasley… - 2023 - researchsquare.com
… , 25-mer MOMP overlapping peptides were tested with sera … the Chlamydia trachomatis
major outer membrane protein can … Maza, LM Increased immunoaccessibility of MOMP epitopes …

Cellular Basis for the Enhanced Efficacy of the Fms-Like Tyrosine Kinase 3 Ligand (FL) Adjuvanted VCG-Based Chlamydia abortus Vaccine

S Richardson, F Medhavi, T Tanner, S Lundy… - Frontiers in …, 2021 - frontiersin.org
… Genome sequencing of C. abortus has revealed the presence of 18 pmp genes as opposed
… and immunogenic outer membrane protein that is expressed throughout the chlamydial