Immunogenicity of TNF-inhibitors

S Atiqi, F Hooijberg, FC Loeff, T Rispens… - Frontiers in …, 2020 - frontiersin.org
… drew attention toward the immunogenicity of TNFi showed a … immunogenicity adequate
drug level measurements are essential. In this review these different aspects of immunogenicity

What is the clinical relevance of TNF inhibitor immunogenicity in the management of patients with rheumatoid arthritis?

P Mehta, JJ Manson - Frontiers in Immunology, 2020 - frontiersin.org
… making interpretation of immunogenicity data from published … monitoring (TDM) and
immunogenicity testing have not been … relevance of TDM and immunogenicity testing of TNFis in …

Personalized medicine in rheumatoid arthritis: How immunogenicity impacts use of TNF inhibitors

C Bodio, C Grossi, F Pregnolato, EG Favalli… - Autoimmunity …, 2020 - Elsevier
… Our study confirms that ETA displays the lowest immunogenicity in comparison to IFX and
… clinical response, further supporting that immunogenicity plays a role in secondary failure to …

Pharmacological strategies for mitigating anti-TNF biologic immunogenicity in rheumatoid arthritis patients

CA Fernandez - Current opinion in pharmacology, 2023 - Elsevier
immunogenicity. In this review, we highlight the limitations of MTX for mitigating TNFα inhibitor
immunogenicity, … for decreasing the risk of immunogenicity during TNFα inhibitor therapy …

Methotrexate and TNF inhibitors affect long-term immunogenicity to COVID-19 vaccination in patients with immune-mediated inflammatory disease

RH Haberman, S Um, JE Axelrad, RB Blank… - The Lancet …, 2022 - thelancet.com
… , TNF inhibitors (especially in combination with methotrexate) led to further decreased rates
of immunogenicity … Most initial studies did not demonstrate any effect of TNF inhibitors on …

Immunogenicity of biologic agents in rheumatology

V Strand, J Goncalves, JD Isaacs - Nature Reviews Rheumatology, 2021 - nature.com
… Furthermore, infliximab (the only chimeric monoclonal antibody among the five available
TNF inhibitors) is more immunogenic than any of the other four TNF inhibitors 4 (Table 1). …

Immunogenicity of subcutaneous TNF inhibitors and its clinical significance in real-life setting in patients with spondyloarthritis

J Hiltunen, P Parmanne, T Sokka, T Lamberg… - Rheumatology …, 2022 - Springer
… and ADAb in SpA patients using TNF inhibitors with the exception of etanercept is useful both
… showed that therapeutic drug monitoring of TNF inhibitors leads to better clinical response …

Immunogenicity of BNT162b2 mRNA SARS-CoV-2 vaccine in patients with psoriatic arthritis on TNF inhibitors

V Venerito, P Stefanizzi, M Fornaro, F Cacciapaglia… - RMD open, 2022 - rmdopen.bmj.com
… This study analyses the immunogenicity of the BNT162b2 vaccine in patients with PsA on
TNFi, … Like recent reports,9 the immunogenicity of BNT162b2 was not hindered in patients with …

Immunogenicity of the COVID-19 mRNA vaccine in adolescents with juvenile idiopathic arthritis on treatment with TNF inhibitors

D Dimopoulou, G Vartzelis, F Dasoula… - Annals of the …, 2022 - ard.bmj.com
… was to evaluate the immunogenicity of the BNT162b2 COVID… Blood samples for the evaluation
of vaccine immunogenicity … on comparison of the immunogenicity between the different …

BAFF predicts immunogenicity in older patients with rheumatoid arthritis treated with TNF inhibitors

B Hernández-Breijo, V Navarro-Compán… - Scientific Reports, 2021 - nature.com
Immunogenicity related to treatment with TNF inhibitors (TNFi… role in the development of
immunogenicity. The objective of … factor (BAFF) with immunogenicity after 6 months of TNFi …