Current advancements and future perspectives of immunotherapy in colorectal cancer research
… Immunotherapy has shown long time remission in a subset of metastatic CRC patients. The
molecular mechanism and emerging roles of immunotherapy in colorectal cancer … are going …
molecular mechanism and emerging roles of immunotherapy in colorectal cancer … are going …
Immunotherapy in colorectal cancer: current and future strategies
A Ooki, E Shinozaki, K Yamaguchi - … of the Anus, Rectum and Colon, 2021 - jstage.jst.go.jp
… at overcoming tumor resistance in current immunotherapy approaches are underway. A better
… In this review, we summarize the most recent advances in immunotherapy based on the …
… In this review, we summarize the most recent advances in immunotherapy based on the …
Landscape of immunotherapy options for colorectal cancer: current knowledge and future perspectives beyond immune checkpoint blockade
A Gorzo, D Galos, SR Volovat, CV Lungulescu, C Burz… - Life, 2022 - mdpi.com
… colorectal cancer has been observed to have a prolonged benefit to immune checkpoint
inhibitors. As a result, pembrolizumab and … on immunotherapy in the colorectal cancer setting, …
inhibitors. As a result, pembrolizumab and … on immunotherapy in the colorectal cancer setting, …
Immunotherapy for early stage colorectal cancer: a glance into the future
… We will then summarize data that might support the development of ICI in localized colorectal
cancer … In this review, we will focus on the key issues at stake in the development of ICI for …
cancer … In this review, we will focus on the key issues at stake in the development of ICI for …
Immunotherapy for colorectal cancer: mechanisms and predictive biomarkers
… we discuss the preclinical and clinical development of immunotherapy for treatment of colorectal
cancer … We also consider open questions including optimal combination treatments and …
cancer … We also consider open questions including optimal combination treatments and …
Immunotherapy: recent advances and its future as a neoadjuvant, adjuvant, and primary treatment in colorectal cancer
I Yu, A Dakwar, K Takabe - Cells, 2023 - mdpi.com
… Immune checkpoint inhibitors are a class of immunotherapy … the efficacy and timing of
immunotherapy for other subsets of … we aim to examine the three main classes of immunotherapy …
immunotherapy for other subsets of … we aim to examine the three main classes of immunotherapy …
[HTML][HTML] Advances in immunotherapy for MMR proficient colorectal cancer
H Lote, N Starling, R Pihlak, M Gerlinger - Cancer treatment reviews, 2022 - Elsevier
… different immunotherapy approaches [13]. In this review, we evaluate recent immunotherapy
… We summarize data that identifies likely reasons for the low success rates and how these …
… We summarize data that identifies likely reasons for the low success rates and how these …
Biomarkers of response and resistance to immunotherapy in microsatellite stable colorectal cancer: toward a new personalized medicine
N Huyghe, E Benidovskaya, P Stevens… - Cancers, 2022 - mdpi.com
… Immunotherapy of Cancer, assessed the Immunoscore assay in 2681 patients with TNM stage
I–III colon cancer (… and centers (r = 0·97 for colon tumor; r = 0.97 for invasive margin; p < 0·…
I–III colon cancer (… and centers (r = 0·97 for colon tumor; r = 0.97 for invasive margin; p < 0·…
Current treatments of metastatic colorectal cancer with immune checkpoint inhibitors—2020 update
G Jung, D Benítez-Ribas, A Sánchez… - Journal of clinical …, 2020 - mdpi.com
… Despite the overall excellent tolerability, anecdotally one case of pneumonitis was
reported related to pembrolizumab and we found one case report in the literature of a severe …
reported related to pembrolizumab and we found one case report in the literature of a severe …
Combinatorial immunotherapies for metastatic colorectal cancer
E Janssen, B Subtil, F de la Jara Ortiz, HMW Verheul… - Cancers, 2020 - mdpi.com
… Unfortunately, colorectal cancer (CRC) has so far been mostly refractory to … In this review,
we give an immuno-oncological overview for this disease and describe immunotherapeutic …
we give an immuno-oncological overview for this disease and describe immunotherapeutic …