[HTML][HTML] Cytokine changes in fatal cases of paraquat poisoning

JS Yen, IK Wang, CC Liang, JF Fu, YC Hou… - American journal of …, 2021 - ncbi.nlm.nih.gov
after paraquat treatment in mice [38]. Interestingly, another study showed that systemic
administration of GM-CSF in mice exposed to paraquat … the immunotoxicity of paraquat [46]. …

[HTML][HTML] Paraquat induced oxidative stress, DNA damage, and cytotoxicity in lymphocytes

S Alizadeh, G Anani-Sarab, H Amiri, M Hashemi - Heliyon, 2022 - cell.com
Paraquat caused dose-dependent DNA damage in peripheral lymphocyte cells and … /kg bw
of paraquat by gavage. The gradual exposure to a dose of 300 mg/kg bw of paraquat showed …

… based on a combination of toxicological experiments and in silico predictions to investigate the adverse outcome pathway (AOP) of paraquat neuro-immunotoxicity

C Zhang, G Shi, Q Meng, R Hu, Y Li, G Hu… - Journal of Hazardous …, 2024 - Elsevier
… in the substantia nigra of C57BL/6 J adult mice after exposure to 30 mg/kg MPTP-HCl for 2
h… can lead to behavioral abnormalities and cognitive impairments following chronic exposure. …

Depletion of NK cells attenuates paraquat-induced acute lung injury by manipulating macrophage polarization

M Wu, C Zhou, M Li, H Yu, D Zhao, W Xue, L Qin… - International …, 2020 - Elsevier
… The median survival time of isotype control group mice was 77.5 h after administrating a
lethal dose of PQ. Pre-injection of anti-asialo-GM1 or anti-NK1.1 significantly prolonged the …

The herbicide paraquat-induced molecular mechanisms in the development of acute lung injury and lung fibrosis

R Subbiah, RR Tiwari - Critical reviews in Toxicology, 2021 - Taylor & Francis
The herbicide paraquat (PQ; 1,1’-dimethyl-4,4’-bipyridylium dichloride) is a highly toxic
organic heterocyclic herbicide that has been widely used in agricultural settings. Since its …

[HTML][HTML] Paraquat toxicity in different cell types of Swiss albino mice

B Onur, K Çavuşoğlu, E Yalçin, A Acar - Scientific Reports, 2022 - nature.com
… Although the mechanisms of Paraquat are not fully … the toxic effects of Paraquat on Swiss
albino mice using physiological, … effects of Paraquat and also the interaction of Paraquat with …

A potential mechanism clue to the periodic storm from microglia activation and progressive neuron damage induced by paraquat exposure

G Shi, C Zhang, X Bai, J Sun, KD Wang… - Environmental …, 2024 - Wiley Online Library
… Minocycline ameliorates paraquat (PQ)-induced nonmotor and motor function of mice in each
group. … neurons by microglial immunotoxicity by activating the CD11b/PI3K/NOX2 pathway. …

Paraquat modulates immunological function in bone marrow-derived macrophages

P Srinontong, J Wandee… - Acta Veterinaria …, 2022 - akjournals.com
… The immunotoxicity of PQ to macrophages is still poorly understood… development of treatments
for reducing paraquat toxicity. … The mice were euthanized with carbon dioxide and cervical …

A potential clue of IL-17A as a helper assist paraquat and T cell infiltration into brain parenchyma

G Shi, K Wang, R Hu, Y Li, Y Jiao, Y Li, Y Li, A Qi… - 2024 - researchsquare.com
… peripheral immune responses means immune dysfunction in mice after PQ exposure. 240
… and usually poses 447 a threat to persons with chronic exposure. The onset of PD is often a …

[PDF][PDF] Effects of paraquat dichloride on adult male wistar rat. an approach in the toxicity of body weights and hematological tissues

GI Edo - J Anal Pharm Res, 2022 - pdfs.semanticscholar.org
… of cancer, and other chronic illnesses associated with the … paraquat dichloride given at 1,
0,1 and 0,001mg/kg doses for 21 days, the immunotoxic effect has been studied in Balbc/ mice