… Genetic heterogeneity also influences the distribution of stromal architecture or the
function of individual tumors and, in turn, may affect prognosis and treatment (26,27). CRC …

… an approximately 14% 5-year survival rate. While early-stage … p53 impact the prognosis of
patients and have implications … to EGFR inhibitors, whereas RAS-wild type tumors may show …

… Patients with a CMS4 cancer had worse survival in the high-… This effect was explained
by the poor outcome for patients … -like tumors (CMS2/3) there is a predictive value for anti-EGFR …

… of prognostic and predictive implications. BRAF alterations in … effects, including cell growth,
proliferation, and survival, and is … is more sensitive to BRAF, MEK, and EGFR inhibition than …

… reduction of their expression can enhance the effect of DNA-… implicated in colorectal cancer
proliferation, survival, resistance, … The synergic antiproliferative effect of HER2 and EGFR …

… strategies to improve prognosis and survival. BRAF and KRAS … The effects of treatment
without an anti-EGFR agent are … expression were downregulated after EMICORON treatment, …

… miR-31-3p expression could be the witness of the tumor’s EGFR … detrimental effect of
cetuximab, both on disease free survival … -EGFR mAbs plus chemotherapy as the first line …

… impact on the practice of oncology for the treatment of mCRC. … PD-1/PD-L1 expression is
often used as a predictive … and monoclonal antibodies directed to the EGFR, as well as ICI …

… and inhibiting EGFR expression, and assays using the EGFR … the five-year survival rate of
patients diagnosed in the advanced … EGFR and thus affect the proliferation of colorectal cancer …

… in colorectal cancer and can also have implications in the … survival (OS) in patients with stage
III or IV colorectal cancer [21]… -EGFR therapy (HR 0.2, 95% CI: 0.1–0.5) in colorectal cancer …