The pathophysiology of distal renal tubular acidosis
CA Wagner, R Unwin, SC Lopez-Garcia… - Nature Reviews …, 2023 - nature.com
… other organs, including bone, liver and skeletal muscle. The … Cl − /HCO 3 − exchanger,
pendrin (also known as SLC26A4)… of the CAII inhibitor acetazolamide. Topiramate causes RTA …
pendrin (also known as SLC26A4)… of the CAII inhibitor acetazolamide. Topiramate causes RTA …
Potential novel role of membrane-associated carbonic anhydrases in the kidney
SK Lee, WF Boron, R Occhipinti - International Journal of Molecular …, 2023 - mdpi.com
… permit rapid interconversion of CO 2 and bicarbonate (HCO 3 − ), … For example, CA II
can be easily blocked by acetazolamide (… , we systematically review CA expression, sub-cellular …
can be easily blocked by acetazolamide (… , we systematically review CA expression, sub-cellular …
[PDF][PDF] DIURETIC MEDICATION AND ITS THERAPEUTIC EFFECT: A SHORT REVIEW
… 5 Similar to how the Cl—HCO3- exchanger pendrin (SLC26A4) is … [9] Oral 125, 200, and
500 mg acetazolamide tablets are … Even though the ammonium chloride loading test can be …
500 mg acetazolamide tablets are … Even though the ammonium chloride loading test can be …
Mechanisms and physiological relevance of acid-base exchange in functional units of the kidney
… The dietary alkaline load is initially converted to bicarbonate in the liver. … IC-β are marked by
apical expression of pendrin SLC26A4, … The adaptation can be supported by acetazolamide …
apical expression of pendrin SLC26A4, … The adaptation can be supported by acetazolamide …
[HTML][HTML] Pathophysiology, Evaluation and Management of Metabolic Acidosis
M Tinawi - Archives of Clinical and Biomedical Research, 2021 - fortuneonline.org
… via an apical Cl - -HCO 3 − exchanger (SLC26A4 protein [pendrin]) … When ammonia is
metabolized in the liver, HCO 3 − is … with sodium bicarbonate delays progression of chronic kidney …
metabolized in the liver, HCO 3 − is … with sodium bicarbonate delays progression of chronic kidney …
[HTML][HTML] Pathophysiology, evaluation, and management of metabolic alkalosis
M Tinawi - Cureus, 2021 - ncbi.nlm.nih.gov
… SLC26A4 encodes for pendrin, which is expressed by the thyroid … In some patients, such as
those with heart failure or liver … a large dose of acetazolamide (500-1000 mg) twice daily IV. …
those with heart failure or liver … a large dose of acetazolamide (500-1000 mg) twice daily IV. …
The therapeutic importance of acid-base balance
BN Quade, MD Parker, R Occhipinti - Biochemical pharmacology, 2021 - Elsevier
… only a mouse-click away from claims that baking soda, lemon juice, and apple cider
vinegar … of baking soda (sodium bicarbonate). Furthermore, we discuss the side effects of …
vinegar … of baking soda (sodium bicarbonate). Furthermore, we discuss the side effects of …
Thiazides induce glucose intolerance through inhibition of mitochondrial carbonic anhydrase 5b in β-cells
P Kucharczyk, G Albano, C Deisl, S Wueest, D Konrad… - bioRxiv, 2022 - biorxiv.org
… (CA) inhibition with acetazolamide and independent of … , the Na + -driven Cl - /bicarbonate
exchanger NDCBE (also … a compensatory reduction in hepatic insulin clearance at time point 0…
exchanger NDCBE (also … a compensatory reduction in hepatic insulin clearance at time point 0…
The Effect of Add-on Acetazolamide to Conventional Diuretics for Diuretic-resistant Edema Complicated with Hypercapnia: A Report of Two Cases
T Inoue, M Hisamichi, D Ichikawa, Y Shibagaki… - Internal …, 2022 - jstage.jst.go.jp
… At this point, the cardiac and liver function was normal. … bicarbonate can stimulate
ventilation, so acetazolamide can … The Cl-/ HCO3- exchanger pendrin (SLC26A4) is located in …
ventilation, so acetazolamide can … The Cl-/ HCO3- exchanger pendrin (SLC26A4) is located in …
Effects of thiazides and new findings on kidney stones and dysglycemic side effects
M Bargagli, MA Anderegg, DG Fuster - Acta Physiologica, 2024 - Wiley Online Library
… CA, leading to the detection of acetazolamide (AZM) in 1950 (… , the chloride bicarbonate
exchanger pendrin (SLC26A4) seems … and causes visceral and hepatic fat accumulation: the …
exchanger pendrin (SLC26A4) seems … and causes visceral and hepatic fat accumulation: the …