Expression of Toll-like Receptors on the Immune Cells in Patients with Common Variable Immune Deficiency after Different Schemes of Influenza Vaccination

AM Kostinova, EA Latysheva, NK Akhmatova… - Viruses, 2023 - mdpi.com
immunodeficiency (CVID) was studied and compared (… The main treatment for patients with
impaired antibody synthesis is … role in cross-priming naive CD8 T cells, which subsequently …

Gain-of-function defects in toll-like receptor 8 shed light on the interface between immune system and bone marrow failure disorders

J Bleesing - Frontiers in Immunology, 2022 - frontiersin.org
… and progenitor cells, and impaired neutrophil differentiation and … +/CD8+ T cells were not
naïve T cells but rather TEMRAs (T-… Summarized, genetic mosaicism, immunodeficiency, and …

Toll-like receptor (TLR) 7 and TLR8 stimulation of mucosal-associated invariant T cells and gamma delta T cells: a role in HIV susceptibility

Z Richard - 2023 - mspace.lib.umanitoba.ca
toll-like receptor (TLR) 7/8 stimulation may lead to the increased activation, depletion, and
impaired functionality of MAIT cells … of a closely related simian immunodeficiency virus (SIV) …

Toll-like receptor signaling in the establishment and function of the immune system

J Aluri, MA Cooper, LG Schuettpelz - Cells, 2021 - mdpi.com
… of naïve T cells into antigen-specific Th1 effector T cells [39]. … pathway effector genes to
specific immunodeficiencies. … from affected individuals similarly displayed impaired response

The immune dysregulation of common variable immunodeficiency disorders

SL Fernando, HSI Jang, J Li - Immunology Letters, 2021 - Elsevier
… -onset severe immunodeficiency with clinical signs of T cell dysfunction … of T and B cell,
toll-like, costimulatory and cytokine receptors. … (<200 cells/uL) and/or impaired in vitro lymphocyte

Common variable immunodeficiency disorders, T-cell responses to SARS-CoV-2 vaccines, and the risk of chronic COVID-19

R Ameratunga, H Longhurst, R Steele, K Lehnert… - The Journal of Allergy …, 2021 - Elsevier
… , malignancy, immunodeficiency, renal, and pulmonary impairment are at … Toll-like receptors
are rendered ineffective. Virus-encoded proteins cloak viral RNA and RIG-like receptors

Toll-like receptor agonists enhance HIV-specific T cell response mediated by plasmacytoid dendritic cells in diverse HIV-1 disease progression phenotypes

MR Jimenez-Leon, C Gasca-Capote… - …, 2023 - thelancet.com
… dendritic cells (pDCs) sense viral and bacterial products through Toll-like receptor (TLR)-7
and -9 and translate this sensing into Interferon-α (IFN-α) production and T-cell activation. The …

Distinct CD8 T cell populations with differential exhaustion profiles associate with secondary complications in common variable immunodeficiency

A Klocperk, D Friedmann, AE Schlaak, S Unger… - Journal of Clinical …, 2022 - Springer
… Our goal was to analyze CD8 T cell homeostasis in patients with infection only … Impaired
CD8+ T cell responses upon Toll-like receptor activation in common variable immunodeficiency

[PDF][PDF] … T lymphocytes is related to inflammation and number of CD8+ T cells expressing programmed cell death protein-1 in common variable immunodeficiency

…, M Siedlar, M Korkosz, T Grodzicki - Folia Medica …, 2020 - psjd.icm.edu.pl
CD8+ T cells expressing PD-1 is associated with lymphadenopathy and number of regulatory
T cells … a marker of exhausted CD8+ T cells with impaired function [15], but CD8+PD-1+ T

B-and T-cell subset abnormalities in monogenic common variable immunodeficiency

S Fekrvand, S Khanmohammadi… - Frontiers in …, 2022 - frontiersin.org
receptors (BCRs), T cell receptors (TCRs) and Toll-likeT cells does not alter the proliferation
or T cell response to antigen, and … T cell-related responses are due to the impaired TB cell