Are alterations in skeletal muscle mitochondria a cause or consequence of insulin resistance?
… role of altered substrate oxidation by the mitochondria as a … insulin action is impaired, eg,
with insulin-resistant participants. … 31 P MRS, was decreased in insulin-resistant offspring [97], …
with insulin-resistant participants. … 31 P MRS, was decreased in insulin-resistant offspring [97], …
Mitochondrial dysfunction, insulin resistance, and potential genetic implications: potential role of alterations in mitochondrial function in the pathogenesis of insulin …
P Sangwung, KF Petersen, GI Shulman… - …, 2020 - academic.oup.com
… in muscle biopsy samples obtained from the insulin resistant … function in healthy, young,
lean, insulin resistant offspring of … deficiency leads to impaired mitochondrial function and …
lean, insulin resistant offspring of … deficiency leads to impaired mitochondrial function and …
Dissociation of muscle insulin resistance from alterations in mitochondrial substrate preference
… HFD)-fed insulin-resistant rats did not manifest altered muscle … in muscle mitochondrial
substrate oxidation explain muscle … the impairments in insulin-stimulated glucose oxidation we …
substrate oxidation explain muscle … the impairments in insulin-stimulated glucose oxidation we …
Revisiting the contribution of mitochondrial biology to the pathophysiology of skeletal muscle insulin resistance
SM Frangos, DJ Bishop, GP Holloway - Biochemical Journal, 2021 - portlandpress.com
… enzymes involved in substrate oxidation. In support of this … impair mitochondrial bioenergetics
or induce skeletal muscle … present in obese/insulin resistant skeletal muscle also has the …
or induce skeletal muscle … present in obese/insulin resistant skeletal muscle also has the …
Altered mitochondrial metabolism in the insulin‐resistant heart
M Makrecka‐Kuka, E Liepinsh, AJ Murray… - Acta …, 2020 - Wiley Online Library
… oxidative stress, impaired cytosolic and mitochondrial … ).146, 147 In the oxidative muscle
cells the diffusion of adenine … alter metabolic substrate oxidation in the cardiac mitochondria of …
cells the diffusion of adenine … alter metabolic substrate oxidation in the cardiac mitochondria of …
Mitochondrial utilization of competing fuels is altered in insulin resistant skeletal muscle of non-obese rats (Goto-Kakizaki)
… in insulin-resistant skeletal muscle results in impaired … white fiber types in control and
insulin-resistant skeletal muscle. … contribution of substrate oxidation to the mitochondrial …
insulin-resistant skeletal muscle. … contribution of substrate oxidation to the mitochondrial …
Dyslipidemia, insulin resistance, and impairment of placental metabolism in the offspring of obese mothers
M Bucher, KRC Montaniel, L Myatt… - … origins of health and …, 2021 - cambridge.org
… and insulin resistant from … impaired mitochondrial function.Petersen et al. have shown that
insulin resistance in the skeletal muscle of healthy, young, lean but insulin-resistant offspring …
insulin resistance in the skeletal muscle of healthy, young, lean but insulin-resistant offspring …
… diet aggravates fructose-induced mitochondrial damage in skeletal muscles and causes differentiated adaptive responses on lipid metabolism in adult male offspring
J Woyames, AFP Souza, RA Miranda… - The Journal of nutritional …, 2022 - Elsevier
… substrate by this tissue in many metabolic conditions [8]. In fact, high-fructose ingestion
can impair muscles … ultrastructure of skeletal muscle of male adult offspring in a fiber type-specific …
can impair muscles … ultrastructure of skeletal muscle of male adult offspring in a fiber type-specific …
A maternal high-fat/low-fiber diet impairs glucose tolerance and induces the formation of glycolytic muscle fibers in neonatal offspring
C Hu, Y Yang, M Chen, X Hao, S Wang, L Yang… - European Journal of …, 2021 - Springer
… muscle fiber types and mitochondrial function in offspring is … tolerance and muscle fiber
types in neonatal offspring and … to impair the glucose tolerance in the neonatal offspring, with …
types in neonatal offspring and … to impair the glucose tolerance in the neonatal offspring, with …
Mitochondrial dysfunction in skeletal muscle contributes to the development of acute insulin resistance in mice
H Lee, TY Ha, CH Jung, FS Nirmala… - … and Muscle, 2021 - Wiley Online Library
… IR is an important risk factor for type 2 diabetes, coronary heart … studies of obese and
insulin-resistant individuals who had … In this study, we show that impaired mitochondrial function …
insulin-resistant individuals who had … In this study, we show that impaired mitochondrial function …