Epigenetics regulation of prostate cancer: Biomarker and therapeutic potential
R Ragavi, P Muthukumaran, S Nandagopal… - … Oncology: Seminars and …, 2023 - Elsevier
… tool to discover novel potential biomarkers and drug targets. As per … Below we describe
individual genes identified as prognostic … methylation of IGFBP3 in CaP and highgrade prostate …
individual genes identified as prognostic … methylation of IGFBP3 in CaP and highgrade prostate …
A modern era of personalized medicine in the diagnosis, prognosis, and treatment of prostate cancer
VK Lakshmanan, S Ojha, Y Do Jung - Computers in Biology and Medicine, 2020 - Elsevier
… NGS is used to identify the novel gene mutations, insertions and deletions (InDels), copy
number variations (CNV), structural variations, and epigenetic alterations with high precision …
number variations (CNV), structural variations, and epigenetic alterations with high precision …
Senescence-associated secretory phenotype constructed detrimental and beneficial subtypes and prognostic index for prostate cancer patients undergoing radical …
… , we used VGF, IGFBP3 and ANG to establish detrimental and … risk subtypes and risk scores,
we identified BCR-free survival-… of PCa through methylation [82]. These findings suggest that …
we identified BCR-free survival-… of PCa through methylation [82]. These findings suggest that …
[HTML][HTML] Methylation biomarkers for early cancer detection and diagnosis: Current and future perspectives
J Ibrahim, M Peeters, G Van Camp… - … Journal of Cancer, 2023 - Elsevier
… identify 759 CpG sites, including 15 located at novel loci, showing an association between
DNA methylation and prostate cancer … whose methylation status could identify cancer samples …
DNA methylation and prostate cancer … whose methylation status could identify cancer samples …
Therapeutic applications of the prostate cancer epigenome
JM Cosgrave, AS Perry - Epigenetic Cancer Therapy, 2023 - Elsevier
… prostate cancer and highlights new frontiers in this field. … and methylation) in neuroendocrine
PCa identified approximately … attractive therapeutic targets. Unlike genetic alterations, DNA …
PCa identified approximately … attractive therapeutic targets. Unlike genetic alterations, DNA …
Application of proteogenomics to urine analysis towards the identification of novel biomarkers of prostate cancer: an exploratory study
… new protein targets for detecting PCa using a proteomics and proteogenomics approach. This
work identified … on comparing and mining the proteome profile of tumor prostate tissue and …
work identified … on comparing and mining the proteome profile of tumor prostate tissue and …
[HTML][HTML] Screening a novel six critical gene-based system of diagnostic and prognostic biomarkers in prostate adenocarcinoma patients with different clinical variables
H Munir, F Ahmad, S Ullah, SM Almutairi… - American Journal of …, 2022 - ncbi.nlm.nih.gov
… In the current study, we identified by microarray technology … other data (promoter methylation
status, genetic alterations, … AND Prostate cancer/adenocarcinoma” and “Hub genes AND …
status, genetic alterations, … AND Prostate cancer/adenocarcinoma” and “Hub genes AND …
[HTML][HTML] Unravelling The Genomic Maze: Bioinformatics Unleashes Insights into Sotos Syndrome (Cerebral Gigantism)
R Sharma, S Kaur, V Gupta, H Grover, K Rao… - Health Sciences …, 2024 - Elsevier
… Drug repurposing, the practice of identifying new therapeutic … mining approaches to identify
potential therapeutic targets … to insulin-like growth stimulus, methylation regulation (H3-K9)…
potential therapeutic targets … to insulin-like growth stimulus, methylation regulation (H3-K9)…
[HTML][HTML] Application of multi-omics techniques to androgenetic alopecia: Current status and perspectives
Y Li, T Dong, S Wan, R Xiong, S Jin, Y Dai… - Computational and …, 2024 - Elsevier
… and metabolites have been identified in individuals with AGA… syndrome, hypertension, and
prostate cancer. This suggests the … ITGB1, IGFBP3, and THBS were subsequently selected as …
prostate cancer. This suggests the … ITGB1, IGFBP3, and THBS were subsequently selected as …
Systems Biomedicine Oriented Multi-Omics Data Integration to Unveil Molecular Signatures and Repositioned Therapeutics in Pituitary Neuroendocrine Tumors
B Aydın - 2021 - search.proquest.com
… ingenious vehicles to identify attractive molecular targets for novel therapies. Not only at
the … There are several biomarker-targeted studies based on methylation profiling being …
the … There are several biomarker-targeted studies based on methylation profiling being …