Salsolinol—neurotoxic or Neuroprotective?
M Kurnik-Łucka, G Latacz, A Martyniak, A Bugajski… - Neurotoxicity …, 2020 - Springer
… examples of (RS)-salsolinol levels in different food products … racemate) was sufficient to
reach a pharmacologically relevant … (RS)-salsolinol is one of the many tetrahydroisoquinoline …
reach a pharmacologically relevant … (RS)-salsolinol is one of the many tetrahydroisoquinoline …
Neuroprotective Activity of Enantiomers of Salsolinol and N-Methyl-(R)-salsolinol: In Vitro and In Silico Studies
… Salsolinol (1-methyl-1,2,3,4-tetrahydroisoquinoline-6,7-diol) … position, and its presence in
vivo, both in humans and rodents… Clearly, in vitro, SAL also exerts its biological action in a dose-…
vivo, both in humans and rodents… Clearly, in vitro, SAL also exerts its biological action in a dose-…
The mechanism of action of salsolinol in brain: implications in Parkinson's disease
… 1-Methyl-6,7dihydroxy-1,2,3,4-tetrahydroisoquinoline (salsolinol) is toxic to dopaminergic …
as a phenolic component in powdered cocoa and cocoa-based products. J Agric Food Chem …
as a phenolic component in powdered cocoa and cocoa-based products. J Agric Food Chem …
N-Methyl-(R)salsolinol and Enzymes Involved in Enantioselective Biosynthesis, Bioactivation, and Toxicity in Parkinson's Disease
M Naoi, W Maruyama - Handbook of Neurotoxicity, 2023 - Springer
… This chapter presents the characteristics of enzymes in the … R)salsolinol synthase catalyzes
the synthesis of (R)salsolinol … converts (R)salsolinol into 2(N)-methyl-(R)salsolinol, and an …
the synthesis of (R)salsolinol … converts (R)salsolinol into 2(N)-methyl-(R)salsolinol, and an …
[HTML][HTML] Ethanol-dependent synthesis of salsolinol in the posterior ventral tegmental area as key mechanism of ethanol's action on mesolimbic dopamine
V Bassareo, R Frau, R Maccioni, P Caboni… - Frontiers in …, 2021 - frontiersin.org
… As a consequence of the oral administration of a pharmacologically relevant dose of ethanol…
-1,2,3,4-tetrahydroisoquinoline (salsolinol), untraceable under control conditions, product of …
-1,2,3,4-tetrahydroisoquinoline (salsolinol), untraceable under control conditions, product of …
Salsolinol induces Parkinson's disease through activating NLRP3-dependent pyroptosis and the neuroprotective effect of acteoside
Y Wang, S Wu, Q Li, W Lang, W Li, X Jiang, Z Wan… - Neurotoxicity …, 2022 - Springer
… We found that several biological pathways were enriched using the KEGG enrichment
analysis. The pathways most significantly correlated to SAL challenges were involved in the NOD-…
analysis. The pathways most significantly correlated to SAL challenges were involved in the NOD-…
Altered urinary tetrahydroisoquinoline derivatives in patients with Tourette syndrome: reflection of dopaminergic hyperactivity?
P Capetian, V Roessner, C Korte, S Walitza… - Journal of Neural …, 2021 - Springer
… reaction or enzymatically via salsolinol synthase (Fig. 1) (… We found elevated levels of
NSAL in the urine of TS patients … to be confirmed in studies with drug-naïve TS patients. NSAL …
NSAL in the urine of TS patients … to be confirmed in studies with drug-naïve TS patients. NSAL …
Enteric Neurotoxicity and Salsolinol
M Kurnik-Łucka, K Gil - Handbook of Neurotoxicity, 2023 - Springer
… of salsolinol in the urine of Parkinsonian patients treated with L-DOPA medication.
Salsolinol is a tetrahydroisoquinoline … Salsolinol and isosalsolinol: Condensation products of …
Salsolinol is a tetrahydroisoquinoline … Salsolinol and isosalsolinol: Condensation products of …
Enteric Neurotoxicity and Salsolinol
M Kurnik-Łucka, K Gil - Handbook of Neurotoxicity, 2021 - Springer
… of salsolinol in the urine of Parkinsonian patients treated with L-DOPA medication. Salsolinol
is a tetrahydroisoquinoline … Salsolinol is either synthesized endogenously via nonenzymatic …
is a tetrahydroisoquinoline … Salsolinol is either synthesized endogenously via nonenzymatic …
[PDF][PDF] Heterocyclic compounds targeting the neurodegenerative diseases
MG Gonzalez - theses.cz
… dysfunction in both salsolinol and glutamate degeneration model… biological activity such as
antagonism on androgen receptor. … Salsolinol (Sal) is an example of tetrahydroisoquinolines (…
antagonism on androgen receptor. … Salsolinol (Sal) is an example of tetrahydroisoquinolines (…