[HTML][HTML] Dopamine and dopamine-related ligands can bind not only to dopamine receptors
J Myslivecek - Life, 2022 - mdpi.com
… Nafadotride is usually considered a highly potent and competitive, centrally active D 3 DR
antagonist (… Functional correlates of dopamine D3 receptor activation in the rat in vivo and their …
antagonist (… Functional correlates of dopamine D3 receptor activation in the rat in vivo and their …
A Historical Perspective on the Dopamine D3 Receptor
P Sokoloff, B Le Foll - Therapeutic Applications of Dopamine D3 Receptor …, 2022 - Springer
… by nafadotride, a partially selective D3 receptor antagonist, at low … ) and measurement of in
vivo D3 receptor occupancy in rats, … It was suggested that higher D3 receptor occupancy may …
vivo D3 receptor occupancy in rats, … It was suggested that higher D3 receptor occupancy may …
[HTML][HTML] Neuronal dopamine D3 receptors: translational implications for preclinical research and CNS disorders
B Kiss, I Laszlovszky, B Krámos, A Visegrády, A Bobok… - Biomolecules, 2021 - mdpi.com
… Prototypical D3R preferring antagonists with D2 receptorial actions, such as nafadotride …
visualization/imaging of D3R and its in vivo occupancy following drug treatment. Obviously, [ 11 …
visualization/imaging of D3R and its in vivo occupancy following drug treatment. Obviously, [ 11 …
[PDF][PDF] TRANSLATIONAL IMPLICATIONS OF NEURONAL DOPAMINE D3 RECEPTORS FOR PRECLINICAL RESEARCH AND CNS DISORDERS
S Bhandari, B Chauhan, N Gupta, A Tripath, S Tripsthy… - afjbs.com
… had comparable in vitro proclivity for D2 and D3 receptors, yet … Nafadotride and U99194,
two prototypical D3R preferring … Occupancy of brain dopamine D3 receptors and drug craving: …
two prototypical D3R preferring … Occupancy of brain dopamine D3 receptors and drug craving: …
The role of dopamine D3 receptors in the mechanism of action of cariprazine
F Calabrese, FI Tarazi, G Racagni, MA Riva - CNS spectrums, 2020 - cambridge.org
… Effects of dopamine D3 receptor antagonists on spontaneous … rats: comparative study with
nafadotride, U 99194A and SB … In vivo occupancy of dopamine D3 receptors by antagonists …
nafadotride, U 99194A and SB … In vivo occupancy of dopamine D3 receptors by antagonists …
Dopamine D3 receptor, cognition and cognitive dysfunctions in neuropsychiatric disorders: from the bench to the bedside
SA Torrisi, F Geraci, G Contarini, S Salomone… - … Dopamine D3 Receptor …, 2022 - Springer
The dopamine D3 receptor (D3R) plays a prominent role in the modulation of cognition in
healthy individuals, as well as in the pathophysiological mechanism underlying the cognitive …
healthy individuals, as well as in the pathophysiological mechanism underlying the cognitive …
The role of dopamine D3 receptors in tobacco use disorder: a synthesis of the preclinical and clinical literature
… the dopaminergic system to treat substance use disorders. Dopamine has 5 receptor subtypes
(… Given the localization and safety profile of the dopamine receptor D3 (DRD3), it is of …
(… Given the localization and safety profile of the dopamine receptor D3 (DRD3), it is of …
[HTML][HTML] Neurobiological and pharmacological perspectives of D3 receptors in Parkinson's disease
The discovery of the D3 receptor (D3R) subtypes of dopamine (DA) has generated an
understandable increase in interest in the field of neurological diseases, especially Parkinson’s …
understandable increase in interest in the field of neurological diseases, especially Parkinson’s …
[HTML][HTML] Arrestin-3 agonism at dopamine D3 receptors defines a subclass of second-generation antipsychotics that promotes drug tolerance
S Schamiloglu, E Lewis, CM Keeshen… - Biological …, 2023 - Elsevier
… also have high affinity for the dopamine D 3 receptor (D3R) (8… distinguish between D2R
and D3R occupancy (9). Though … -biased SGA to an ex vivo slice of mouse PFC modulates Ca …
and D3R occupancy (9). Though … -biased SGA to an ex vivo slice of mouse PFC modulates Ca …
[HTML][HTML] Dopamine D3 Receptor Plasticity in Parkinson's Disease and L-DOPA-Induced Dyskinesia
K Lanza, C Bishop - Biomedicines, 2021 - mdpi.com
… In humans, in vivo imaging of D2-like receptors with [ 11 C] … with D3R, D3nf decreases the
capacity of D3R to interact with … (ST 198) and less specific (nafadotride) D3R antagonist also …
capacity of D3R to interact with … (ST 198) and less specific (nafadotride) D3R antagonist also …