Induction of antigen-specific tolerance in T cell mediated diseases
L Passerini, S Gregori - Frontiers in Immunology, 2020 - frontiersin.org
… tolerogenic arm of the immune system would restore the immune homeostasis and control
the … by tolDC are promising tools for the reprogramming of pathogenic T cells and induction of …
the … by tolDC are promising tools for the reprogramming of pathogenic T cells and induction of …
Tissue‐Targeted Drug Delivery Strategies to Promote Antigen‐Specific Immune Tolerance
Y Rui, HB Eppler, AA Yanes… - Advanced healthcare …, 2023 - Wiley Online Library
… for high concentrations of immune cells to encounter each other… for immune reprogramming
could promote antigen-specific … key immune cell subsets involved in the induction of immune …
could promote antigen-specific … key immune cell subsets involved in the induction of immune …
Inducing immune tolerance with dendritic cell-targeting nanomedicines
A Cifuentes-Rius, A Desai, D Yuen… - Nature …, 2021 - nature.com
… leverages the cells and function of the immune system to quell … of isolating and reprogramming
dendritic cells (DCs), central … antigen-specific immune tolerance is achieved by inducing T …
dendritic cells (DCs), central … antigen-specific immune tolerance is achieved by inducing T …
Precision engineering of an anti-HLA-A2 chimeric antigen receptor in regulatory T cells for transplant immune tolerance
… cells or by the recipient mice. Altogether, we demonstrate that genome-engineered mono-antigen-specific
A2-… and exhibit antigen-dependent in vivo suppression, independent of TCR …
A2-… and exhibit antigen-dependent in vivo suppression, independent of TCR …
[PDF][PDF] Treg-based immunotherapy for antigen-specific immune suppression and stable tolerance induction: a perspective
S Sakaguchi, R Kawakami… - Immunotherapy …, 2023 - academic.oup.com
… strategies for Treg-based immune suppression and the issues to be resolved for achieving
stable antigen-specific immune suppression and tolerance … The recipient immune system …
stable antigen-specific immune suppression and tolerance … The recipient immune system …
[HTML][HTML] Immune tolerance induced by immune-homeostatic particles
… Immune tolerance, a status of immune system unreacted to … and successive precise T cell
programming process. Extensive … and autoantigens to induce antigen-specific Tregs have been …
programming process. Extensive … and autoantigens to induce antigen-specific Tregs have been …
Nanoparticle platforms for antigen-specific immune tolerance
… nanoparticles to antigen-specific immune cell subsets (84). This effectively mimics the function
of the … Additional strategies for reprograming antigen-exposed dendritic cells for immune …
of the … Additional strategies for reprograming antigen-exposed dendritic cells for immune …
Cell fate reprogramming in the era of cancer immunotherapy
O Zimmermannova, I Caiado, AG Ferreira… - Frontiers in …, 2021 - frontiersin.org
… technologies for generation of immune cells by cell fate … As their natural role lies in the
maintenance of self-tolerance, … ability to activate antigen-specific cytotoxic T-cells via antigen cross-…
maintenance of self-tolerance, … ability to activate antigen-specific cytotoxic T-cells via antigen cross-…
Restoring tumor immunogenicity with dendritic cell reprogramming
… cells to evade the immune system. We used the minimal gene regulatory network of type
1 conventional dendritic cells (cDC1) to reprogram cancer cells … in vitro tumor antigen–specific …
1 conventional dendritic cells (cDC1) to reprogram cancer cells … in vitro tumor antigen–specific …
Lymph node-targeted synthetically glycosylated antigen leads to antigen-specific immunological tolerance
… induce antigen-specific immunological tolerance, and investigate the molecular mechanisms
of tolerance. … as downstream effects on the antigen-specific T cell response. We furthermore …
of tolerance. … as downstream effects on the antigen-specific T cell response. We furthermore …