… the liver as very low-density lipoproteins (amiodarone, amineptine, tetracycline, stavudine
and tianeptine) or increased … In summary, phospholipidosis is a multifactorial phenomenon …

… in drug-induced phospholipidosis, we investigated EVs release in amiodarone-treated HEK-…
it accumulates in tissues during chronic dosing, namely in liver [20,40]. Over the last decade, …

… liver cells, more typically causing macrovesicular steatosis and sometimes microvesicular
steatosis or phospholipidosis … and in the liver of mice in vivo, amiodarone potently activates the …

… , increasing lysosomal pH, and causing structural and functional changes in the cellular
organelles characteristic of phospholipidosis … to have accumulated in the liver, kidney, and brain […

… Another form of fat accumulation, phospholipidosis, is … a potentially more severe liver injury
and is linked to more acute … , doxycycline, and amiodarone cause severe alterations in the …

… in hepatic cells may cause an increase in ROS which leads to … of lysosomal lipids and
leads to phospholipidosis, this … with amiodarone showed an elevation in liver enzymes like …

… effects are more likely with long-term use of amiodarone. … Amiodarone has been associated
with hepatic transaminitis, … by N-DEA), phospholipidosis, immunological mechanisms, and …

… Although two related side effects of amiodarone therapy, increased CT liver density and
secondary phospholipidosis, were reported 34 years ago[16], the relationship between iodine …

… From these observations and from the physicochemical properties of amiodarone, we …
Furthermore, we demonstrate that measurement of amiodarone autofluorescence is highly …

… Cortical neurons and astrocytes are more sensitive to amiodarone than liver and kidney
cell lines. We confirmed the inhibition of EBP enzyme by analyzing the sterol intermediates in …