… for IL-23 in the development of chronic inflammatory autoimmune diseases characterized by
… the biological features of IL-23 and gathered recent research on the role of IL-23 in fibrotic …

… with inflammatory bowel disease or psoriasis … interleukin-23 and interleukin-12 through
subunit p40. However, only one study has linked spontaneous anti–interleukin-12 with severe …

… and Metabolic Diseases Mild and severe PsOs are both associated with an increased risk of
… and stroke, while severe PsO is associated with a significantly increased risk of CV mortality …

… more severe inflammatory disease in one study.Genetic absence of IL-17A was also reported
to increase the severity of … made no difference or improved disease activity parameters and …

… of IL‐23 and its specific receptor, IL‐23R, in the pathogenesis of several chronic inflammatory
diseases has … This review focuses on IL‐23R expression and regulation in immune cells. …

… 2004 that IL-23 promoting IL-17 production is linked to multiple … [6], suggesting a role
for the Th17 pathway in human diseases. … with moderate–severe psoriasis: ustekinumab (anti-IL-12/…

… with severe and non-severe disease. IL-23 and FCal were significantly higher in severe CD
… diagnostic role of IL-23 was superior to FCal in discriminating between severe and mild to …

… Guselkumab significantly achieved and maintained a higher psoriasis area and severity …
The aim of the present work was to assess cutaneous IL-23R expression in psoriasis and PsA …

… gene polymorphisms in the interleukin-23 receptor (IL23R) and interleukin 17A (IL17A…
diseases, severe liver and kidney disease, cardiovascular, cerebrovascular and endocrine disease…

… disease and comorbidity. Psoriasis has been identified as a risk factor for cardiovascular
and metabolic disease, and increasing … As an example, increased levels of IL ‐23 and IL ‐23R …