… cells according to their IL-23 receptor (IL-23R) expression and contribution to IL-17A production
in … -23A knockout prevented blood pressure elevation in a severe model of hypertension, …

… Alopecia areata is characterized by rapid onset of hair loss as a single patch on the scalp
to complete loss of all body hair in severe cases [2]. The incidence of this disease is estimated …

… Considering that the tubular atrophy/interstitial fibrosis in IgAN can better evaluate the
disease severity, IgAN patients were classified into three groups according to the Oxford …

… of the IL-23–IL-17 axis in disease initialization and severity. … the levels of IL-23 were not
correlated with disease activity or other … IL-23p19 subunit expression was also increased in both …

… showed that IL-23R (rs10889677 A/C) was associated with AS … diseases we studied, IL-23R
(rs10889677 A/C) increased the … AA genotype increased the risk of autoimmune diseases in …

… , causes the development of severe histological changes in … the role of IL23R A/A genotype
in mucosal expression IL-23 in … to more evaluate the role of these polymorphisms in IL-23/IL-…

… disorders (10-18); thus we hypothesized that the serum IL-23 level might be associated with
PE or its severity… In this study, we detected a significant association between IL-23 levels of …

… , with higher scores indicating greater extent or severity of psoriasis) at week 16. … severe
disease). PASI scores range from 0 to 72, with higher scores indicating greater extent or severity …

… disease severity, as defined by higher … More likely, these results suggest a different role of
IL-17A in IBD, specifically, protective rather than pathogenic. In mice, IL-17A or IL-17 receptor …

… reduced disease severity (day 7) (Fig. 1B); as expected, the Il23p19 −/− chimeric mice (Il23p19
−/− →Il23p19 −/− ) did not develop pain throughout and have reduced disease severity, …