An overview of reprogramming approaches to derive integration-free induced pluripotent stem cells for prospective biomedical applications

C Dey, K Raina, KK Haridhasapavalan, M Thool… - Recent advances in …, 2021 - Elsevier
… study reprogrammed blood-derived endothelial progenitor cells … Hence, for efficient
protein-based reprogramming, TLR3 … Although protein-based reprogramming is the safest and a …

Induced pluripotent stem cells: reprogramming platforms and applications in cell replacement therapy

A Al Abbar, SC Ngai, N Nograles, SY Alhaji… - BioResearch open …, 2020 - liebertpub.com
… the reprogramming of induced pluripotent stem cells (iPSCs), the roles of the OSKM in
reprogramming the mature differentiated cells … and drawbacks of the reprogramming strategies. In …

Reprogramming stem cells in regenerative medicine

J Mao, Q Saiding, S Qian, Z Liu, B Zhao… - Smart …, 2022 - Wiley Online Library
… are multipotent stem cells derived from adult somatic cells. … of human ESCs-like stem cells
derived from different adult cells (eg, … to reprogram, although protein-based methods are less …

RNA-based strategies for cell reprogramming toward pluripotency

A Bailly, O Milhavet, JM Lemaitre - Pharmaceutics, 2022 - mdpi.com
… program of somatic cells towards pluripotency at … reprogramming of murine fibroblasts into
cells with properties similar to ESCs [4]. These cells were called induced pluripotent stem cells

Current reprogramming methods to generate high-quality iPSCs

Y Cha, P Leblanc, CH Kim, JS Schweitzer… - Methods in iPSC …, 2021 - Elsevier
Induced pluripotent stem cell (iPSC) technology that could revert the fate of terminally
differentiated somatic cells into embryonic stem cell… of protein-based reprogramming are still much …

[图书][B] Generation of human ipscs by protein reprogramming and stimulation of Tlr3 signaling

C Liu, M Ameen, S Himmati, D Thomas, N Sayed - 2021 - Springer
protein-based nuclear reprogramming in human fibroblasts, and we found that efficient
nuclear reprogramming of human fibroblasts to pluripotency … -induced pluripotent stem cells (…

[HTML][HTML] Non-integrating methods to produce induced pluripotent stem cells for regenerative medicine: An overview

I Belviso, V Romano, D Nurzynska… - … and functional tissue …, 2020 - intechopen.com
Protein-based reprogramming carries the advantage that it does not cause any genetic
changes. As already mentioned, current methods of protein-based reprogramming are less …

Potential of induced pluripotent stem cells for use in gene therapy: History, molecular bases, and medical perspectives

A Fus-Kujawa, B Mendrek, A Trybus, K Bajdak-Rusinek… - Biomolecules, 2021 - mdpi.com
Induced pluripotent stem cells (iPSCs) are defined as reprogrammed somatic cells exhibiting
embryonic stem cell characteristics. Since their discovery in 2006, efforts have been made …

Induced pluripotent stem cells: hope in the treatment of diseases, including muscular dystrophies

D Gois Beghini, S Iwao Horita, CM Cascabulho… - International journal of …, 2020 - mdpi.com
… efficiency was not reported in this study, it is known that iPS cells induced by micro-RNAs
have a reprogramming efficiency above 10% and also have the lowest tumorigenicity rate. …

[HTML][HTML] Enhanced efficiency of generating human-induced pluripotent stem cells using Lin28-30Kc19 fusion protein

B Son, H Yoon, J Ryu, H Lee, J Joo… - … in Bioengineering and …, 2022 - frontiersin.org
… -induced pluripotent stem cell (hiPSC) generation in respect of AP-positive colonies, via
protein-based … a significant advancement in the field of protein-based reprogramming research. …