Carbachol and nicotine in prefrontal cortex have differential effects on sleep-wake states

A Parkar, DC Fedrigon, F Alam, G Vanini… - Frontiers in …, 2020 - frontiersin.org
… the infusion of carbachol (1 mM) or nicotine (100 mM) into … of the carbachol-induced
seizures (occurring at 10 mM). The … prefrontal cortex and pontine reticular formation, wherein …

Lesioning of the pedunculopontine nucleus reduces rapid eye movement sleep, but does not alter cardiorespiratory activities during sleep, under hypoxic conditions in …

AM Fink, LA Burke, K Sharma - Respiratory physiology & neurobiology, 2021 - Elsevier
… regulatory center in the pons that may be implicated in the … 0.9 % saline rinse followed by an
infusion of 10 % formalin to fix … mixed cholinergic agonist, carbachol, into the PPT—caused a …

Physiology of normal sleep

JM Monti, AS BaHammam… - Sleep and …, 2022 - Springer
… Furthermore, direct infusion of a 5-HT 1A receptor agonist into the … carbachol or the
anticholinesterase agent physostigmine and neostigmine into the pontine reticular formation induces

… -and cholinergic-inputs from substantia nigra and pedunculo-pontine tegmentum, respectively, converge in amygdala to modulate rapid eye movement sleep in rats

RK Yadav, BN Mallick - Neuropharmacology, 2021 - Elsevier
… Effects of microinjection of Carbachol bilaterally into Amygdala… We observed that infusion
of either DA- or ACh-agonist into … that the electrical stimulation induced effects were due to …

Neurobiology of sleep

IJ Raphael, M Pedemonte - Sleep Neurology: A Comprehensive Guide to …, 2021 - Springer
… whose consumption would induce forgetfulness and flowing … (and slow wave sleep),
whereas micro-infusions of an MCH … This system includes the reticular formation, the reticularis …

Rapid Eye Movement Sleep and Dream Sleep

BN Mallick - … Translational Research: From Disease Diagnosis to …, 2022 - Springer
reticular formation activation-induced waking (… induce expression of otherwise REMS-loss
associated changes (symptoms). Indeed, infusion of picrotoxin (Pic), a GABA-antagonist, into

Neural and homeostatic regulation of REM sleep

SH Park, F Weber - Frontiers in psychology, 2020 - frontiersin.org
within the pons might not be required for REM sleep, … directly contribute to the induction of
REM sleep. Research in the … in REM sleep, which could be reversed by infusion of the GABA-…

A century searching for the neurons necessary for wakefulness

FS Grady, AD Boes, JC Geerling - Frontiers in neuroscience, 2022 - frontiersin.org
… concept of a diffuse “reticular activating system,” the past century … , such as infusing an
exogenous neurotransmitter, receptor … or caudal pons had EEG rhythms reflecting a normal sleep-…

Neural and Homeostatic Regulation of Rapid Eye Movement Sleep by the Preoptic Area and Tuberomammillary Nucleus

JJ Maurer - 2024 - search.proquest.com
… Intracranial injections of carbachol, a non-specific cholinergic agonist, into the pons of cats
or rats cause muscle atonia and induces REMs (George et al., 1964; Baghdoyan et al., 1984; …

Molecular mechanisms of REM sleep

RG Yamada, HR Ueda - Frontiers in Neuroscience, 2020 - frontiersin.org
… The pons of the brainstem contains a population of REM-on … PnO is a region of the brainstem
reticular formation which is … Notably, carbachol-induced depolarization of hippocampal …