[HTML][HTML] Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity

S Verdura, E Cuyàs, E Cortada, J Brunet… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
… Consequently, they typically exhibit low T-cell infiltration and … driver of immune checkpoint
signaling in tumor cells is a largely … T-cell activation events as the induction of T-cell-mediated …

[HTML][HTML] Protective effects of resveratrol against 5-fluorouracil-induced oxidative stress and inflammatory responses in human keratinocytes

S Chen, N Tamaki, Y Kudo, T Tsunematsu… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
… Nrf2 signaling and inhibiting NF-κB signaling, respectively. … (2) 5-FU blocks DNA replication
and induces the … the stability and activity of Nrf2, suppresses apoptosis and resistance to …

[PDF][PDF] Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis

J Suh, H Kim, J Min, HJ Yeon, M Hemberg… - Cell Reports …, 2024 - cell.com
… However, chondrosarcoma cells frequently exhibit marked … enhance the induction of cell
death in chondrosarcoma cells. … and antiapoptotic signals of chondrosarcoma cells via the …

Mass spectrometric investigations of caloric restriction mimetics

MJ Bibyk, MJ Campbell, AB Hummon - Proteomics, 2021 - Wiley Online Library
Resveratrol activates sirtuin-1, which is a protein that regulates cancer promotion/… cells,
resveratrol has shown anti-cancer activity by blocking cellular growth and inducing apoptosis [26]…

MiR-128-3p mediates TNF-α-induced inflammatory responses by regulating Sirt1 expression in bone marrow mesenchymal stem cells

L Wu, G Zhang, C Guo, X Zhao, D Shen… - … and biophysical research …, 2020 - Elsevier
… Up-regulation of sirtuin 1 induced by resveratrol also … -128-3p targets sirtuin 1 to mediate
the TNF-α-induced inflammatory … gingivalis-induced inflammatory response via p38 signaling

[HTML][HTML] Epigenetic Abnormalities in Chondrosarcoma

M Bereza, M Dembiński, AE Zając, J Piątkowski… - International Journal of …, 2023 - mdpi.com
… a reduction in the antitumor activity of RUNX3. APOBEC3B … ability of resveratrol was confirmed
in vivo by using a CS cell … the cell cycle [92], was observed to induce apoptosis and cell

[PDF][PDF] Genome-wide screens reveal that resveratrol induces replicative stress in human cells

Y Benslimane, T Bertomeu, J Coulombe-Huntington… - Molecular Cell, 2020 - cell.com
human cells treated with the natural product resveratrol pinpointed DNA replication stress
induction as a major anti-proliferative effect of resveratrol. … histone deacetylase sirtuin 1, which …

Natural Sirtuin Modulators in Drug Discovery: A Review (2010-2020)

Y Chang, KY Yeong - Current Medicinal Chemistry, 2021 - ingentaconnect.com
… The anti-cancer effect elicited can be rationalised to the … Resveratrol treatment at 5 μg/μL
reduced cell death induced by p25 … 3 signaling pathway by activating sirtuin 1 in SW1353 …

Lockdown of mitochondrial Ca2+ extrusion and subsequent resveratrol treatment kill HeLa cells by Ca2+ overload

RV Devi, D Raj, M Doble - The International Journal of Biochemistry & Cell …, 2021 - Elsevier
… and the cells with Ca 2+ ions thereby inducing cell death. … Activation of apoptosis through
several signalling pathways as … the anticancer effect of RESV and NCLX on HeLa cells in …

Polyphenolic molecules targeting STAT3 pathway for the treatment of cancer

MA Aziz, MS Sarwar, T Akter, MS Uddin, S Xun, Y Zhu… - Life Sciences, 2021 - Elsevier
Signal transducer and activator of transcription 3 (STAT3) is a ubiquitously-expressed
signaling molecule in almost all body cells… the cellular proliferation, differentiation, cell cycle …