[PDF][PDF] Sirt1 suppresses MCP-1 production during the intervertebral disc degeneration by inactivating AP-1 subunits c-Fos/c-Jun.

WT Cai, P Guan, MX Lin, B Fu… - European Review for …, 2020 - europeanreview.org
… Sirt1 expression through the Sirt1 activator resveratrol (Res) or … physicochemical factors or
intracellular signaling cascades, c-… 34a/sirtuin 1 pathway contributes to apoptosis induced by …

[HTML][HTML] Therapeutic single compounds for osteoarthritis treatment

H Lee, X Zhao, YO Son, S Yang - Pharmaceuticals, 2021 - mdpi.com
… Moreover, although natural extracts exhibit minimal safety … -activated protein kinase, and
sirtuin-1 protein expression was … Resveratrol can also induce p53 protein degradation in a …

[PDF][PDF] Sirtfoods: New Concept Foods, Functions, and Mechanisms. Foods 2022, 11, 2955

OD Akan, D Qin, T Guo, Q Lin, F Luo - 2022 - researchgate.net
… The genistein–daidzein mixture induced cell apoptosisresveratrol activated SIRT1 in
human chondrosarcoma cells, … H.; Zhao, JH MiR-34a/sirtuin-1/foxo3a is involved in genistein …

The bifunctional roles of sirtuins and their therapeutic potential in cancer

YT Lee, YJ Tan, PY Mok, AV Subramaniam… - … in Cancer and Metabolic …, 2021 - Elsevier
… SIRT2 exhibits antitumor properties mainly through … in CRC cells suppressed the
BKM120-induced cell apoptosis by inhibiting the … Suramin showed anticancer activities by …

[HTML][HTML] Role of plant-derived active constituents in cancer treatment and their mechanisms of action

AW Khan, M Farooq, M Haseeb, S Choi - Cells, 2022 - mdpi.com
… Furthermore, the apoptotic cell death is induced by these … It exhibits a pro-apoptotic effect in
colon cancer and has a … a key role in the anticancer activities of resveratrol. For this purpose, …

[HTML][HTML] Polyphenols as a diet therapy concept for endometriosis—current opinion and future perspectives

A Gołąbek, K Kowalska, A Olejnik - Nutrients, 2021 - mdpi.com
… naringenin induced ROS-mediated cell death and inhibited cell … In an in vitro study, resveratrol
induced a concentration-… Natural polyphenols exhibit a pleiotropic action profile and could …

[PDF][PDF] International Journal of Aging Research (ISSN: 2637-3742)

P Datri - Journal of Aging Research, 2021 - academia.edu
… (PARP) and sirtuin 1 (SIRT1) in various pathological … as antitumor activity, including the
induction of apoptosis by … (Warburg effect), the antitumor activity shown by resveratrol caused, at …

… protects against mitochondrial dysfunction in atherosclerosis (AS) mice with chronic unpredictable mild stress (CUMS) via SIRT1/PGC-1α/TFAM/LON signaling …

H Shi, M Sun, S Wang, F He, R Yang, Z Li… - Journal of …, 2024 - Elsevier
… Besides, resveratrol significantly increased the ATP levels … -1α/TFAM/Lon signaling pathway.
The current study possesses … signaling pathway for the treatment of chronic stress-induced

Targeting crosstalk of signaling pathways in cancer stem cells: A promising approach for development of novel anti-cancer therapeutics

S Bhal, CN Kundu - Medical Oncology, 2023 - Springer
cell activates β-catenin signaling, leading to Hh-inducedSirtuin-1(SIRT1) is a type of
NAD-dependent class III histone … of MALAT1 through Resveratrol treatment restrains nuclear …

[PDF][PDF] Hyperglycemia induced C2C12 myoblast cell cycle arrest and skeletal muscle atrophy by modulating sirtuins gene expression in rats

P Surinlert, T Thitiphatphuvanon… - Polish journal of …, 2021 - bibliotekanauki.pl
… Tang CH, Yang RS, Liu SH (2017) Induction of sirtuin-1 signaling by resveratrol induces
human chondrosarcoma cell apoptosis and exhibits antitumor activity. Sci Rep 7: 3180. Chen Y, …