[HTML][HTML] Phytochemicals mediate autophagy against osteoarthritis by maintaining cartilage homeostasis
Z Tian, X Zhang, M Sun - Frontiers in Pharmacology, 2021 - frontiersin.org
… apoptosis by modulating autophagy-related signaling … induction of the Sirtuin-1 (SIRT-1)
pathway, thus protecting … water, and in addition, resveratrol is chemically unstable when …
pathway, thus protecting … water, and in addition, resveratrol is chemically unstable when …
[HTML][HTML] Trans-Resveratrol: From Phytonutrient Supplement, to Novel Nanotherapeutic Agent
TL Harney - Periodontology-New Insights, 2022 - intechopen.com
… The researchers in this study used qPCR and biochemical pathway analysis to examine
96 genes, present in human neuroblastoma cells, that were induced into inflammation via the …
96 genes, present in human neuroblastoma cells, that were induced into inflammation via the …
Emerging natural-product-based treatments for the management of osteoarthritis
ML Pérez-Lozano, A Cesaro, M Mazor, E Esteve… - Antioxidants, 2021 - mdpi.com
… Resveratrol induced osteoblast differentiation by regulating autophagy and modulating the
Sirt1/Runx-2/Fox-O1 and PI3K/AKT/mTOR signaling … Ginsenosides exhibit a large variety of …
Sirt1/Runx-2/Fox-O1 and PI3K/AKT/mTOR signaling … Ginsenosides exhibit a large variety of …
Targeting energy metabolism in cancer treatment
J Kubik, E Humeniuk, G Adamczuk… - International journal of …, 2022 - mdpi.com
… on induction of metabolism disturbance of tumor cells as a … that resveratrol induces apoptosis
in melanoma cells through … shows anti-tumor activity in various types of cancer cells with …
in melanoma cells through … shows anti-tumor activity in various types of cancer cells with …
A Network-Based Transcriptomic Landscape of HepG2 Cells to Uncover Causal Gene Cytotoxicity Interactions Underlying Drug-Induced Liver Injury
LS Wijaya, A Gabor, IE Pot, L van de Have… - bioRxiv, 2023 - biorxiv.org
… the high cell death-correlated modules with the cell death … Transcriptomic perturbations
in the HepG2 cell line exhibit … that are contributing to cell signaling based on availability in a …
in the HepG2 cell line exhibit … that are contributing to cell signaling based on availability in a …
[PDF][PDF] A literature review of bioactive substances for the treatment of periodontitis: In vitro, in vivo and clinical studies
… Resveratrol is a natural non-flavonoid polyphenolic … , anti-inflammatory, and anticancer
activities [164]. Silymarin … -κB signaling pathways in a rat model of periodontitis induced by …
activities [164]. Silymarin … -κB signaling pathways in a rat model of periodontitis induced by …
Mitochondrial metabolism as a dynamic regulatory hub for malignant transformation and anticancer drug resistance
… Cancerous cells with KRAS mutations exhibit enhanced … participates in the cell death pathway
through caspase induction [60]… the phosphorylation of SIRT1 or sirtuin 1 (silent mating type …
through caspase induction [60]… the phosphorylation of SIRT1 or sirtuin 1 (silent mating type …
Histone modification as a potential preventative and therapeutic approach for cardiovascular disease
JS Habibian, BS Ferguson - Histone Modifications in Therapy, 2020 - Elsevier
… the fetal gene program or exhibit hypertrophic responses in the … signals and fetal gene
reactivation without inducing cell … response to phenylephrine-induced hypertrophic stress. Sirt3 is …
reactivation without inducing cell … response to phenylephrine-induced hypertrophic stress. Sirt3 is …
A Recent Update on the Epigenetic Repertoire and Chromatin Modifying Therapy in Diabetes Mellitus: A Comprehensive Review
X Wang, D Zhao, NM Beeraka… - Current Medicinal …, 2023 - ingentaconnect.com
… For instance, the treatment of resveratrol in diabetic rats … sirtuin-1 (SIRT1) [40, 41], in a
sequence-dependent manner through deacetylation of SF38-K23 peptide [20, 39] and induce …
sequence-dependent manner through deacetylation of SF38-K23 peptide [20, 39] and induce …
[HTML][HTML] Extracellular nicotinamide phosphoribosyltransferase: role in disease pathophysiology and as a biomarker
E Semerena, A Nencioni, K Masternak - Frontiers in Immunology, 2023 - frontiersin.org
… the ER-stress-induced apoptosis of these cells through the … However, as compared to OA,
human RA tissues exhibit … These “early” NAMPTi usually show potent anti-cancer activity in …
human RA tissues exhibit … These “early” NAMPTi usually show potent anti-cancer activity in …