… of DNA vaccine targeting E6 and E7 proteins of human papillomavirus 16 (HPV16) and HPV18 for immunotherapy in combination with recombinant vaccinia boost …
… 16/18 E6/E7-specific CD8 + T cell responses, either alone or in … of HPV 16/18 E6/E7 fusion
proteins by codon optimization in … This effect may be attributed to cytotoxic T lymphocyte (CTL) …
proteins by codon optimization in … This effect may be attributed to cytotoxic T lymphocyte (CTL) …
Enhancement of specific T-lymphocyte responses by monocyte-derived dendritic cells pulsed with E2 protein of human papillomavirus 16 and human p16INK4A
N Sunthamala, N Sankla, J Chuerduangphui… - PeerJ, 2020 - peerj.com
… response to host p16INK4a and HPV E2 is induced via … Here, we aimed to develop human
p16INK4a and HPV16 E2 … The fusion protein HPV-16 E6/E7 and Fms-like tyrosine kinase-…
p16INK4a and HPV16 E2 … The fusion protein HPV-16 E6/E7 and Fms-like tyrosine kinase-…
[HTML][HTML] Human Papillomavirus Type 16 Based L1, L2, E6, and E7 Peptide Microspheres Induce Encapsulated Peptide Mixture Specific Cytotoxic T Lymphocytes and …
MA Khan, K Ali, M Rizvi - Cancer Screening and Prevention, 2024 - xiahepublishing.com
… C57BL/6 origin with the HPV16 E6/E7 virus and the c-Hras oncogene… calreticulin-human
papillomavirus 16 E7 fusion protein … harboring human papillomavirus 16 cytotoxic T lymphocyte …
papillomavirus 16 E7 fusion protein … harboring human papillomavirus 16 cytotoxic T lymphocyte …
Construction and immune effect of an HPV16/18/58 trivalent therapeutic adenovirus vector vaccine
B Wan, L Qin, W Ma, H Wang - Infectious Agents and Cancer, 2022 - Springer
… and specific cytotoxic T lymphocyte (CTL) and T lymphocyte … fusion gene and HPV58E6E7
fusion gene into U14 cells … , and the vaccine could induce E7-specific CD8 + T cell immunity …
fusion gene into U14 cells … , and the vaccine could induce E7-specific CD8 + T cell immunity …
CUE-101, a novel E7-pHLA-IL2-Fc fusion protein, enhances tumor antigen-specific T-cell activation for the treatment of HPV16-driven malignancies
SN Quayle, N Girgis, DR Thapa, Z Merazga… - Clinical Cancer …, 2020 - AACR
… -specific CD8 + T cells in preclinical studies. In vivo studies confirm selective expansion of
tumor-specific cytotoxic CD8 + T cells, induction … with an E6/E7 vaccination approach resulted …
tumor-specific cytotoxic CD8 + T cells, induction … with an E6/E7 vaccination approach resulted …
Immunoinformatics Design and In Vivo Immunogenicity Evaluation of a Conserved CTL Multi-Epitope Vaccine Targeting HPV16 E5, E6, and E7 Proteins
N Guo, Z Niu, Z Yan, W Liu, L Shi, C Li, Y Yao, L Shi - Vaccines, 2024 - mdpi.com
… epitopes to induce specific cellular immune responses in vivo… vaccine targeting the HPV16
E6/E7 fusion protein, there is … identify 11 conserved cytotoxic T lymphocyte (CTL) epitopes …
E6/E7 fusion protein, there is … identify 11 conserved cytotoxic T lymphocyte (CTL) epitopes …
Combined prophylactic and therapeutic immune responses against human papillomaviruses induced by a thioredoxin-based L2-E7 nanoparticle vaccine
… A variety of E6/E7 antigen formulations has been set-up and tested, … use VLPs as carriers
of early HPV antigens. VLPs containing an L2-E7 fusion protein, and thus capable of inducing …
of early HPV antigens. VLPs containing an L2-E7 fusion protein, and thus capable of inducing …
[PDF][PDF] The Role of Large Extracellular Vesicles in Human Papillomavirus-Associated Immune Modulation of Langerhans Cells
V Ticar - 2021 - ourarchive.otago.ac.nz
… by keratinocytes expressing HPV16 E6/E7 impair LCLC … tissue homeostasis and induce
immune responses. In line with … network and released upon fusion of multivesicular bodies with …
immune responses. In line with … network and released upon fusion of multivesicular bodies with …
Preclinical Immunogenicity and Efficacy Studies for Therapeutic Vaccines for Human Papillomavirus-Type-16-Associated Cancer
M Mohammadi, A Saha, W Giles-Davis, Z Xiang… - Vaccines, 2024 - mdpi.com
… The increased efficacy against E6 + E7 + TC - 1 tumor cell … In tumors, AdC6-gDE7652-induced
E7-specific CD8 + T cells … -terminal segment that within a gD fusion protein is secreted, we …
E7-specific CD8 + T cells … -terminal segment that within a gD fusion protein is secreted, we …
Immune responses to human papillomavirus and the development of human papillomavirus vaccines
M Stanley - Human Papillomavirus, 2020 - Elsevier
… Failure to induce an effective immune response is related to … immune response; this defective
immune response facilitates viral … Bacterially expressed fusion proteins of HPV L1 were …
immune response facilitates viral … Bacterially expressed fusion proteins of HPV L1 were …