… Interestingly, inflammatory infiltrates coexist with fibrotic changes and angiogenesis in OA,
which can be more prevalent in the late stages than in the early stages of the disease 48,54 (…

… Osteoarthritis (OA) is a degenerative joint disease characterized by cartilage degradation,
osteophyte formation, and synovial inflammation [… be induced through angiogenesis. Previous …

Osteoarthritis (OA) is a common disabling disease which has a high incidence rate in the …
extracellular matrix degradation, apoptosis, inflammatory reaction, autophagy and then further …

… structural changes in osteoarthritis (OA) involve synovial inflammation and angiogenesis,
as … ) and interleukin (IL)-8, and the angiogenic factor vascular endothelial growth factor (VEGF). …

… The HMGB1 inhibitor alleviated angiogenic and inflammatory reaction in CFA-induced
TMJOA rats. (A) Histopathological evaluation of HIF-1α, VEGF and CD34 in SD rats’ synovium …

… angiogenesis, tissue damage and inflammation. Hyperglycemia is also directly associated
with the accumulation of advanced glycation end-products (AGEs), which result from a …

Osteoarthritis (OA) pannus contains a network of neovascularization that is formed and maintained
by angiogenesis, which … The adipokine visfatin stimulates the release of inflammatory …

… Hence, subchondral bone angiogenesis emerged in sight as a fresh therapeutic target to …
reducing angiogenesis in different circumstances, such as inflammatory microenvironment and …

… trigger of diseases, including osteoarthritis (OA) and sarcopenia… a pro-inflammatory signature
and higher angiogenic sprouting … systemic inflammation. Overall, our data demonstrate that …

… Synoviocytes isolated from inflamed areas of the OA synovium exhibit high angiogenic …
from adjacent non-inflamed areas 45,46,47 . VEGF promotes synovial angiogenesis via VEGF …