Inflammation and aging: signaling pathways and intervention therapies
… Immunosenescence of neutrophils occurs in a low-grade inflammatory environment, with
specific abnormalities in their metabolism and function, including decreased phagocytic …
specific abnormalities in their metabolism and function, including decreased phagocytic …
Immunosenescence, inflammaging, and frailty: role of myeloid cells in age-related diseases
A Bleve, F Motta, B Durante, C Pandolfo… - Clinical reviews in …, 2022 - Springer
… neutrophils; this critically perpetuates the pro-inflammatory responses [64, 65]. Classically
activated macrophages are professional antigen-presenting cells (APCs) that can stimulate T-…
activated macrophages are professional antigen-presenting cells (APCs) that can stimulate T-…
Immunosenescence and inflammaging in the aging process: age-related diseases or longevity?
… , immunosenescence has been considered detrimental because it may lead to a low-grade,
sterile chronic inflammation … The aged neutrophils (CD10 neg ) are accumulated in the skin …
sterile chronic inflammation … The aged neutrophils (CD10 neg ) are accumulated in the skin …
Interconnections between inflammageing and immunosenescence during ageing
… to significant pro-inflammatory signalling and highlight the … immunosenescence, and
inflammation in driving poor health … and neutrophils, reduced levels of the most pro-inflammatory …
inflammation in driving poor health … and neutrophils, reduced levels of the most pro-inflammatory …
Immunosenescence: molecular mechanisms and diseases
Z Liu, Q Liang, Y Ren, C Guo, X Ge, L Wang… - … and targeted therapy, 2023 - nature.com
… This chronic inflammation is a typical phenomenon linked to immunosenescence and it is
considered the major … Age-regulated tissue-specific macrophages and neutrophils may cause …
considered the major … Age-regulated tissue-specific macrophages and neutrophils may cause …
Immunosuppressive network promotes immunosenescence associated with aging and chronic inflammatory conditions
A Salminen - Journal of Molecular Medicine, 2021 - Springer
… immunosenescence, the occurrence of immunosenescent cells increases in many age-related
diseases … -grade chronic inflammation most probably promotes immunosenescence with …
diseases … -grade chronic inflammation most probably promotes immunosenescence with …
Accelerated immunosenescence, oxidation and inflammation lead to a higher biological age in COPD patients
… Thus, the purpose of the present work was to investigate several functions of circulating
neutrophils (adherence, chemotaxis, phagocytosis and superoxide anion stimulation capacity) …
neutrophils (adherence, chemotaxis, phagocytosis and superoxide anion stimulation capacity) …
How can we improve vaccination response in old people? Part I: Targeting immunosenescence of innate immunity cells
A Aiello, ME Ligotti, M Garnica, G Accardi… - International Journal of …, 2022 - mdpi.com
… This, in turn, reduces the ability of neutrophils to survive longer at the site of inflammation, …
across disease states. It has been suggested that altered functions may represent neutrophil “…
across disease states. It has been suggested that altered functions may represent neutrophil “…
Metabolic pathways in immune senescence and inflammaging: Novel therapeutic strategy for chronic inflammatory lung diseases. An EAACI position paper from the …
F Roth‐Walter, IM Adcock, C Benito‐Villalvilla… - Allergy, 2024 - Wiley Online Library
… inflammatory lung diseases. … inflammation on immune cells and tissue microenvironment
are thus chiefly involved in the pathophysiology of allergic and other immune‐driven diseases. …
are thus chiefly involved in the pathophysiology of allergic and other immune‐driven diseases. …
[HTML][HTML] Immunosenescence and inflamm-aging: clinical interventions and the potential for reversal of aging
… , and, hence, the hallmarks of immunosenescence may be markedly and … Inflammation is
a key component of immunosenescence, … Dysfunction of neutrophils and macrophages as a …
a key component of immunosenescence, … Dysfunction of neutrophils and macrophages as a …