Dysbiosis in inflammatory bowel disease: pathogenic role and potential therapeutic targets

PT Santana, SLB Rosas, BE Ribeiro, Y Marinho… - International journal of …, 2022 - mdpi.com
… the gut microbiota has become a focus of major interest in the study of inflammatory bowel
disease (IBD) pathogenesis. … of several gut microbiome abnormalities in patients with Crohn’s …

Revisiting inflammatory bowel disease: pathology, treatments, challenges and emerging therapeutics including drug leads from natural products

K Yeshi, R Ruscher, L Hunter, NL Daly… - Journal of clinical …, 2020 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic and life-long disease characterized by
gastrointestinal tract inflammation. It is caused by the interplay of the host’s genetic predisposition …

Changing global epidemiology of inflammatory bowel diseases: sustaining health care delivery into the 21st century

AN Ananthakrishnan, GG Kaplan, SC Ng - Clinical Gastroenterology and …, 2020 - Elsevier
… and microbiome on disease pathogenesis and have offered opportunities for disease prevention
by … to provide globally sustainable inflammatory bowel disease care in the 21st century. …

The microbiome in inflammatory bowel diseases: from pathogenesis to therapy

S Liu, W Zhao, P Lan, X Mou - Protein & cell, 2021 - academic.oup.com
Inflammatory bowel disease (IBD) has become a global disease with accelerating incidence
worldwide in the 21st century while its accurate etiology remains unclear. In the past decade…

The epidemiology of inflammatory bowel disease: East meets west

WY Mak, M Zhao, SC Ng… - Journal of gastroenterology …, 2020 - Wiley Online Library
incidence of inflammatory bowel diseases (IBD) in East has risen over the past decade to
become a global disease. … of the estimated prevalence of inflammatory bowel diseases (IBD) …

Depression and anxiety in inflammatory bowel disease: epidemiology, mechanisms and treatment

TH Bisgaard, KH Allin, L Keefer… - Nature reviews …, 2022 - nature.com
… Depression and anxiety are common comorbidities in inflammatory bowel disease (IBD),
but the prevalence varies across studies owing to heterogeneity in study populations and …

The four epidemiological stages in the global evolution of inflammatory bowel disease

GG Kaplan, JW Windsor - Nature reviews Gastroenterology & …, 2021 - nature.com
Inflammatory bowel disease (IBD) is a global disease; its evolution can be stratified into four
epidemiological … The journey from a few sporadic cases of inflammatory bowel disease (IBD) …

From inflammation to colitis-associated colorectal cancer in inflammatory bowel disease: Pathogenesis and impact of current therapies

MC Fantini, I Guadagni - Digestive and Liver Disease, 2021 - Elsevier
… The risk of colorectal cancer (CRC) is higher in patients with inflammatory bowel disease
(IBD). Population-based data from patients with ulcerative colitis (UC) estimate that the risk of …

Inflammatory bowel disease and risk of colorectal cancer: An overview from pathophysiology to pharmacological prevention

M Lucafò, D Curci, M Franzin, G Decorti… - Frontiers in …, 2021 - frontiersin.org
… Increased risk of colorectal cancer (CRC) in inflammatory bowel disease (IBD) patients
has been attributed to long-standing chronic inflammation, with the contribution of genetic …

[HTML][HTML] Twenty-first century trends in the global epidemiology of pediatric-onset inflammatory bowel disease: systematic review

ME Kuenzig, SG Fung, L Marderfeld, JWY Mak… - Gastroenterology, 2022 - Elsevier
… Growing global rates of inflammatory bowel disease will place increasing pressure on …
of pediatric inflammatory bowel disease is important to helping understand its pathogenesis. …