A meta‐analysis of the influence of ADRB2 genetic polymorphisms on albuterol (salbutamol) therapy in patients with asthma

K Hikino, S Kobayashi, E Ota… - British journal of …, 2021 - Wiley Online Library
Albuterol is a β2-adrenergic agonist and has been used for … studies have examined the
β2-adrenergic receptor (ADRB2) … good responses to albuterol therapy were more frequent in …

[HTML][HTML] Impact of 27gln\glu polymorphisms of β2-adrenergic receptor gene on pulmonary function in asthmatic children treated with nebulized salbutamol

HAN Abood - Biomedical and Biotechnology Research Journal …, 2021 - journals.lww.com
… the effect of β2-adrenergic receptor polymorphisms 27Gln\Glu C 79 > G (rs1042714) on the
therapeutic responseresponse to albuterol after chronic use in Argentinean population.[ 25 ] …

The impact of genomic variants on patient response to inhaled bronchodilators: a comprehensive update

MG Matera, P Rogliani, G Novelli… - Expert Opinion on Drug …, 2023 - Taylor & Francis
… It has been reported that C491T polymorphism leads to salbutamol refractoriness in severe
asthmatics … biomarker for β 2 -agonist refractoriness in patients with persistent severe asthma. …

Pharmacogenetics of bronchodilator response: future directions

JE Sordillo, RS Kelly, SM Lutz, J Lasky-Su… - Current allergy and …, 2021 - Springer
… studies of albuterol response in minority populations, effect … SABAs, such as albuterol, act
on beta-2 adrenergic receptorseffect modification by age for genetic polymorphisms in the …

[HTML][HTML] The effect of 16 Arg/Gly β2adrenergic receptors gene polymorphism on pulmonary function in asthmatic children treated with nebulized salbutamol

AS Mohammed, HAA Abood… - … Research Journal (BBRJ …, 2021 - journals.lww.com
… [ 1 ] The disease influence both adults and children, with high morbid and relative little
mortality as compared with other chronic disease.[ 2 , 3 ] Spirometry is the first-line test to …

[HTML][HTML] Association between beta-2 adrenergic receptor variants and clinical outcomes in children and adolescents with acute asthma

FP Muchão, AV Souza, JM Souza… - Einstein (Sao Paulo …, 2022 - SciELO Brasil
… at position 16 determines the clinical severity of chronic obstructive … to albuterol in children
with and without a history of wheezing. J … B2 adrenergic receptor gene polymorphism effect on …

[HTML][HTML] Unraveling the Impact of Salbutamol Polytherapy: Clinically Relevant Drug Interactions

L Marques, N Vale - Future Pharmacology, 2023 - mdpi.com
… : nebulized salbutamol in frequent low doses or IB and salbutamoleffect of salbutamol by
possibly optimizing β-adrenoceptor … gene polymorphisms reduce bronchodilator response, and …

The Effect of Adrenergic β2 Receptor Thr164Ile Gene Polymorphism on Asthma Risk, Severity and Response to Β2 Agonists in Egyptian Children

RM Amer, S Zamzam, KM Salah… - Egyptian Journal of …, 2020 - journals.ekb.eg
… significantly higher in moderate and severe compared to mild asthma … response to inhalation
therapy which can increase asthma morbidity 10. Varying responses to salbutamol as a β2

Variability of the pharmacological response in children with different ADRB2 gene polymorphisms in recurrent bronchial obstruction and bronchial asthma

UI Zakirova, NA Israilova, UN Karimova… - BIO Web of …, 2023 - bio-conferences.org
… The aim of our work was to evaluate the effectiveness of the effect of β2-agonists on …
beta-2adrenergic agonists are the drugs salbutamol (ventolin) and fenoterol (berotek) of prolonged

The role of association of ADRB2 gene polymorphism with therapeutic response to β2-agonists in children with recurrent bronchial obstruction

IA Karimdzhanov, UI Zakirova, GA Yusupova… - 2022 - repository.tma.uz
effect of β2-agonists occurs through β2-adrenergic receptors, … In the case of long-term use
of high doses of β2-agonists, a … was no effect of genotypes on the effect of salbutamol [11]. …