Effect of treadmill exercise on serum corticosterone, serum and hippocampal BDNF, hippocampal apoptosis and anxiety behavior in an ovariectomized rat model of …

R Yakhkeshi, F Roshani, K Akhoundzadeh… - Physiology & Behavior, 2022 - Elsevier
Gene expression was calculated using the 2 –ΔΔCt method. … caspase 3, Bcl-2, and Bax and
the ratio of Bcl-2/Bax. Caspases … a stronger effect of exercise on SPS-exposed rats with more …

[HTML][HTML] Corticosterone and Glucocorticoid Receptor in the Cortex of Rats during Aging—The Effects of Long-Term Food Restriction

V Tesic, J Ciric, I Jovanovic Macura, N Zogovic… - Nutrients, 2021 - mdpi.com
… detrimental effects of chronic exposure to … Aging induced an increase in mRNA expression
of Bcl-2-associated X protein (Bax) (Figure 4B), a pro-apoptotic member of the Bcl-2 gene

[HTML][HTML] The molecular mechanism of chronic high-dose corticosterone-induced aggravation of cognitive impairment in APP/PS1 Transgenic Mice

SQ Zhang, LL Cao, YY Liang, P Wang - Frontiers in Molecular …, 2021 - frontiersin.org
… The data of gene expression were analyzed by the t-test (n = … to detect the expression of
Bcl-2 and Bax in the hippocampus in all … Therefore, the effects of short-term exposure to GCs on …

The role of glucocorticoid receptors in the induction and prevention of hippocampal abnormalities in an animal model of posttraumatic stress disorder

M Araki, M Fuchikami, J Omura, T Miyagi… - …, 2020 - Springer
… , it is conceivable that elevated cortisol/corticosterone levels due to exposure to severe stress
… -PCR to examine the effects of SPS on Bcl-2 and Bax mRNA levels 2 h and 4 h after SPS. …

Changes in Rat Adrenal Cortex and Pineal Gland in Inverted Light–Dark Cycle: A Biochemical, Histological, and Immunohistochemical Study

HA Shawky, SMN Abdel Hafez… - Microscopy and …, 2023 - academic.oup.com
diurnal corticosterone curve. This curve was derived from taking four daily blood samples:
typically done upon waking (30 min after exposure … of BAX and BCL-2 immunostained sections …

[HTML][HTML] Dim blue light at night induces spatial memory impairment in mice by hippocampal neuroinflammation and oxidative stress

Q Liu, Z Wang, J Cao, Y Dong, Y Chen - Antioxidants, 2022 - mdpi.com
… plasma corticosterone level and hippocampal microglia activation… , we detected the mRNA
expression levels of Bdnf, Psd95, … (G) The ratio of BCL-2 and BAX protein expression levels (n …

Delayed behavioral and genomic responses to acute combined stress in zebrafish, potentially relevant to PTSD and other stress-related disorders: Focus on neuroglia …

LE Yang, J Wang, D Wang, G Hu, ZY Liu, D Yan… - Behavioural Brain …, 2020 - Elsevier
… Specifically, one week after adult zebrafish were exposed to a … whole-body cortisol and brain
gene expression, focusing on … 3), suggesting the imbalance between Bcl-2 and Bax in our …

… negatively regulates hippocampal neurogenesis and promote anxious depression-like behavior via upregulating apoptosis and inflammatory signals in adult rats

A Mishra, S Singh, S Singh, V Tiwari, S Chaturvedi… - Brain Research …, 2021 - Elsevier
… that increased levels of corticosterone enhanced depression and … expression of antiapoptotic
protein (Bcl-2) whereas, upregulated protein expression of pro apoptotic mediators (Bax, …

[HTML][HTML] In vitro modeling of the neurobiological effects of glucocorticoids: A review

K Bassil, AC Krontira, T Leroy, AIH Escoto… - Neurobiology of …, 2023 - Elsevier
… GCs (namely CORT; corticosterone in animals or cortisol and hydrocortisone in … corticosterone
0.25 mM 1 h CORT exposure decreases cell viability, ATP levels, MMP, gene expression

[HTML][HTML] Mitochondrial glucocorticoid receptors and their actions

I Kokkinopoulou, P Moutsatsou - International journal of molecular …, 2021 - mdpi.com
… on mtRNA expression as well as the effect of corticosterone (… Bim, thus leading to Bax
activation and triggering mainly the … results in downregulation of GR/Bcl-2 levels in mitochondria. …