Health benefits of astaxanthin against age-related diseases of multiple organs: A comprehensive review
P Alugoju, VKD Krishna Swamy… - Critical Reviews in …, 2023 - Taylor & Francis
… tubular epithelial cells (PTECs) in diabetic nephropathy. … High glucose exposure to
mesangial cells acts as a good in … to prevent high glucose-induced renal fibrosis in mesangial …
mesangial cells acts as a good in … to prevent high glucose-induced renal fibrosis in mesangial …
The emerging role of HDACs: pathology and therapeutic targets in diabetes mellitus
… function in renal mesangial cells in diabetic kidneys [223]. … represents a therapeutic option
in diabetic nephropathy [65]. … found to prevent high glucose-induced myocardial damage …
in diabetic nephropathy [65]. … found to prevent high glucose-induced myocardial damage …
A network pharmacology strategy to investigate the anti-osteoarthritis mechanism of main lignans components of Schisandrae Fructus
L Min, Y Wu, G Cao, D Mi, C Chen - International Immunopharmacology, 2021 - Elsevier
… MMP 13 and collagen II by affecting the SRC-EGFR-MAPK14 … on SRC gene expression in
the right knee cartilage of mice. (K) … inhibit the expression and activity of SRC to inhibit EGFR …
the right knee cartilage of mice. (K) … inhibit the expression and activity of SRC to inhibit EGFR …
Is there a relationship between the prevalence of autoimmune thyroid disease and diabetic kidney
MM Stefanowicz-Rutkowska, W Matuszewski… - degruyter.com
… of diabetic kidney disease (DKD) in patients with diabetes mellitus … Inhibition of Src kinase
blocks high glucose-induced EGFR transactivation and collagen synthesis in mesangial cells …
blocks high glucose-induced EGFR transactivation and collagen synthesis in mesangial cells …
γ peptide nucleic acid-based miR-122 inhibition rescues vascular endothelial dysfunction in mice fed a high-fat diet
… that the inhibition of miR-122 prevents … The high glucose condition decreases eNOS
activation. (69,70) Our results show that miR-122 inhibition partially rescues a high-glucose-induced …
activation. (69,70) Our results show that miR-122 inhibition partially rescues a high-glucose-induced …
ADAM 17 and epithelial-to-mesenchymal transition: the evolving story and its link to fibrosis and cancer
… High glucose (HG) is the base of diabetic nephropathy by determining ECM production in
glomerular mesangial cells… in the transactivation of Notch signalling in liver cancer stem cells, …
glomerular mesangial cells… in the transactivation of Notch signalling in liver cancer stem cells, …
Augmented pulmonary vasoconstrictor reactivity after chronic hypoxia requires Src kinase and epidermal growth factor receptor signaling
CE Norton, JR Sheak, S Yan… - … of respiratory cell and …, 2020 - atsjournals.org
… We confirmed that Src kinase and EGFR inhibition did not alter … stretch-induced NOX activation
in mesangial cells (13). … EGFR is transactivated by a variety of stimuli, including platelet-…
in mesangial cells (13). … EGFR is transactivated by a variety of stimuli, including platelet-…
G Protein-coupled receptor kinase 2 as novel therapeutic target in fibrotic diseases
N Li, S Shan, XQ Li, TT Chen, M Qi, SN Zhang… - Frontiers in …, 2022 - frontiersin.org
… of the liver fibrosis or in high glucose-induced CF (51, 52). … GRK2 activity is essential to
the transactivation of CXCR4 … the proliferation of glomerular mesangial cells, leading to the …
the transactivation of CXCR4 … the proliferation of glomerular mesangial cells, leading to the …
The function of KDEL receptors as UPR genes in disease
ES Wires, KA Trychta, LM Kennedy… - International journal of …, 2021 - mdpi.com
… UPR, cells were treated with an IRE1α kinase inhibitor that … of XBP1 in the mouse substantia
nigra pars compacta was … Src family kinases, in turn, play a role in EGFR transactivation…
nigra pars compacta was … Src family kinases, in turn, play a role in EGFR transactivation…
Pathogenesis of Microvascular Complications
M Khamaisi, GL King, K Park, Q Li - Diabetes Complications …, 2020 - Springer
… may contribute to diabetic nephropathy and retinopathy. Cultured rat mesangial cells (MC)
incubated with high glucose in the … Inhibition of Src kinase blocks high glucose-induced EGFR …
incubated with high glucose in the … Inhibition of Src kinase blocks high glucose-induced EGFR …